About: COVID-19 Critical Illness Pathophysiology Driven by Diffuse Pulmonary Thrombi and Pulmonary Endothelial Dysfunction Responsive to Thrombolysis

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About: COVID-19 Critical Illness Pathophysiology Driven by Diffuse Pulmonary Thrombi and Pulmonary Endothelial Dysfunction Responsive to Thrombolysis Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	COVID-19 Critical Illness Pathophysiology Driven by Diffuse Pulmonary Thrombi and Pulmonary Endothelial Dysfunction Responsive to Thrombolysis
Creator	Powell, Charles Do, Chun, Glen Dangayach, Neha Kohli-Seth, Roopa Olin, Jeffrey Poor, Hooman Serrao, Gregory Tolbert, Thomas Ventetuolo, Corey Zeidman, Amanda
source	MedRxiv; Medline; PMC
abstract	Critically ill COVID-19 patients have relatively well-preserved lung mechanics despite severe gas exchange abnormalities, a feature not consistent with classical ARDS but more consistent with pulmonary vascular disease. Patients with severe COVID-19 also demonstrate markedly abnormal coagulation, with elevated D-dimers and higher rates of venous thromboembolism. We present four cases of patients with severe COVID-19 pneumonia with severe respiratory failure and shock who demonstrated immediate improvements in gas exchange and/or hemodynamics with systemic tPA.
has issue date	2020-04-21(xsd:dateTime)
bibo:doi	10.1101/2020.04.17.20057125
bibo:pmid	32511632
has license	cc-by-nc-nd
sha1sum (hex)	344270e0b71f1c00e2f1f3d5f694af6f61eeecec
schema:url	https://doi.org/10.1101/2020.04.17.20057125
resource representing a document's title	COVID-19 Critical Illness Pathophysiology Driven by Diffuse Pulmonary Thrombi and Pulmonary Endothelial Dysfunction Responsive to Thrombolysis
has PubMed Central identifier	PMC7276060
has PubMed identifier	32511632
schema:publication	medRxiv
resource representing a document's body	covid:344270e0b71f1c00e2f1f3d5f694af6f61eeecec#body_text
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