About: Chapter 9 Keeping Track of Viruses

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Chapter 9 Keeping Track of Viruses
Creator	Murray, Catherine Oh, Thomas Rice, Charles
source	Elsevier; PMC
abstract	Publisher Summary This chapter reviews methods of isolating, identifying, and tracking viruses with potential applications to microbial forensic investigations. Viruses are the most abundant biological entities on earth. These obligate parasites infect every form of life, from archaea and eubacteria to fungi, plants, and animals. Viruses play key roles in global ecology—they form a vast reservoir of genetic diversity, influence the composition and evolution of host populations, and affect the cycling of chemical compounds through the environment. Research has focused on the tiny fraction that causes disease in humans, domestic animals, and crops; sequencing surveys have suggested that the majority of viruses are completely unknown. The ability of viruses to jump species barriers, move between habitats, and circle the globe rapidly underscores the importance of continued vigilance for naturally emerging or deliberately engineered outbreaks. Viruses are extremely simple “life” forms without metabolic capacity, organelles, translational machinery, or autonomous replicative potential. Virus particles constitute a minimal set of components, primarily those required to deliver the genome to the target cell and initiate replication. Consequently, virus particles (or virions) are extremely small, most in the range of 20 to 200 nm in diameter. Virions are diverse not only in size but also in composition, morphology, and genome characteristics. Virus particles may be irregular in shape or possess a distinct symmetry, such as helical or icosahedral. Particles may be surrounded by a host-derived membrane, termed “enveloped,” or a tight protein shell, termed “nonenveloped.”
has issue date	2011-12-31(xsd:dateTime)
bibo:doi	10.1016/b978-0-12-382006-8.00009-8
has license	els-covid
sha1sum (hex)	347cee909f74ffac599a875b75d46c92f0480c61
schema:url	https://doi.org/10.1016/b978-0-12-382006-8.00009-8
resource representing a document's title	Chapter 9 Keeping Track of Viruses
has PubMed Central identifier	PMC7148630
schema:publication	Microbial Forensics
resource representing a document's body	covid:347cee909f74ffac599a875b75d46c92f0480c61#body_text
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