About: Low-dose Whole-lung Irradiation for COVID-19 Pneumonia: Short Course Results

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Low-dose Whole-lung Irradiation for COVID-19 Pneumonia: Short Course Results Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Low-dose Whole-lung Irradiation for COVID-19 Pneumonia: Short Course Results
Creator	Bozorgmehr, Rama Taghizadeh-Hesary, Farzad Mokhtari, Majid Ameri, Ahmad Dehbaneh, Farzad Dehbaneh, Shabanpour Dokht Shoaei, Simin Farahbakhsh, Mohammad Izadi, Amir Izadi, Hossein Kashi, Shabanpour Kashi, Yousefi Nabavi, Mahmood Rahnama, Nazanin Shahram, Amir Shahram, Yousefi Shoaei, Hossein Simin, Dokht Taghizadeh-Hesary,
Source	Elsevier; Medline; PMC
abstract	Abstract Purpose The COVID-19 outbreak is affecting people worldwide. Many of the infected patients suffer from respiratory involvement that may progress to acute respiratory distress syndrome. This pilot study aimed to evaluate the clinical efficacy of low-dose whole-lung radiotherapy in patients with COVID-19 pneumonia. Methods and Materials In this clinical trial, conducted in ***, we enrolled patients with COVID-19 who were older than 60 years and hospitalized to receive supplementary oxygen for their documented pneumonia. Participants were treated with whole-lung irradiation in a single fraction of 0.5 Gy plus the national protocol for the management of COVID-19. Vital signs (including blood oxygenation and body temperature) and laboratory findings (IL-6 and CRP) were recorded before and after irradiation. Results Between 21 May 2020 and 24 June 2020, five patients received whole-lung irradiation. They were followed for 5-7 days to evaluate the response to treatment and toxicities. The clinical and paraclinical findings of four of the five patients (patient #4 became worse and died on day 3) improved on the first day of irradiation. Patient #3 opted-out of the trial on the third day after irradiation. The mean time to discharge was 6 days for the other three patients. No acute radiation-induced toxicity was recorded. Conclusions With a response rate of 80%, whole-lung irradiation in a single fraction of 0.5 Gy had encouraging results in oxygen-dependent patients with COVID-19 pneumonia.
has issue date	2020-07-21(xsd:dateTime)
bibo:doi	10.1016/j.ijrobp.2020.07.026
bibo:pmid	32707264
has license	els-covid
sha1sum (hex)	3507c81f0fa6788a4c5127a9f77df6ff782da58d
schema:url	https://doi.org/10.1016/j.ijrobp.2020.07.026
resource representing a document's title	Low-dose Whole-lung Irradiation for COVID-19 Pneumonia: Short Course Results
has PubMed Central identifier	PMC7373065
has PubMed identifier	32707264
schema:publication	Int J Radiat Oncol Biol Phys
resource representing a document's body	covid:3507c81f0fa6788a4c5127a9f77df6ff782da58d#body_text
is schema:about of	named entity 'COVID-19' named entity 'Pneumonia' named entity 'Low-dose' named entity 'Low-Dose' named entity 'Pneumonia' named entity 'Irradiation' named entity 'supplemental oxygen' named entity 'pneumonia' named entity 'septic shock' named entity 'treatment protocol' named entity 'non-invasive ventilation' named entity 'supportive care' named entity 'radiotherapy' named entity 'chest CT scan' named entity 'thyroid gland' named entity 'body temperature' named entity 'cytokine storm' named entity 'ischemic heart disease' named entity 'hypertension' named entity 'COVID-19' named entity 'clinical findings' named entity 'pneumonia' named entity 'UFH' named entity 'interleukin-6' named entity 'lung' named entity 'macrolides' named entity 'peer-reviewed' named entity 'lung' named entity 'nasopharyngeal swab' named entity 'Karnofsky' named entity 'pneumonia' named entity 'supplemental oxygen' named entity '100 percent' named entity 'blood oxygenation' named entity 'endothelial cells' named entity 'malignancy' named entity 'Ethical code' named entity 'remdesivir' named entity 'facial mask' named entity 'pneumonia' named entity 'pneumonia' named entity 'esophagus' named entity 'photon' named entity 'lungs' named entity 'COVID' named entity 'mechanical ventilation' named entity 'COVID' named entity 'pneumonia' named entity 'CT scanner' named entity 'dexamethasone' named entity 'thrombotic' named entity 'lung' named entity 'cytokine storm' named entity 'crude mortality rate' named entity 'radiation treatment' named entity 'PCR' named entity 'mediastinum' named entity 'cytokine storm' named entity 'body temperature' named entity 'France' named entity 'follow-up' named entity 'nasopharyngeal swab' named entity 'pneumonia'

Faceted Search & Find service v1.13.91 as of Mar 24 2020

Alternative Linked Data Documents: Sponger | ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3229 as of Jul 10 2020, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (94 GB total memory)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software