About: Distinct Characteristics and Complex Evolution of PEDV Strains, North America, May 2013

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About: Distinct Characteristics and Complex Evolution of PEDV Strains, North America, May 2013–February 2014 Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Distinct Characteristics and Complex Evolution of PEDV Strains, North America, May 2013–February 2014
Creator	Marthaler, Douglas Wang, Qiuhong Rovira, Albert Vlasova, Anastasia Culhane, Marie Rossow, Kurt Saif, Linda Collins, James Saif, L Wang, Q Collins, J Culhane, M Marthaler, ( Rossow, K Rovira, A Vlasova, (
Source	Medline; PMC
abstract	Porcine epidemic diarrhea virus (PEDV), which emerged in the United States in 2013, has spread throughout North America. Limited availability of PEDV complete genomes worldwide has impeded our understanding of PEDV introduction into the United States. To determine the relationship between the North American strains and global emerging and historic PEDV strains, we sequenced and analyzed complete genomes of 74 strains from North America; the strains clustered into 2 distinct clades. Compared with the initially reported virulent US PEDV strains, 7 (9.7%) strains from 4 states contained insertions and deletions in the spike gene (S INDELs). These S INDEL strains share 99.8%–100% nt identity with each other and 96.2%–96.7% nt identity with the initial US strains. Furthermore, the S INDEL strains form a distinct cluster within North American clade II, sharing 98.6%–100% nt identity overall. In the United States, the S INDEL and original PEDV strains are co-circulating and could have been introduced simultaneously.
has issue date	2014-10-01(xsd:dateTime)
bibo:doi	10.3201/eid2010.140491
bibo:pmid	25279722
has license	no-cc
sha1sum (hex)	351fca8e4bd7321d75ec0227794deb0db3567540
schema:url	https://doi.org/10.3201/eid2010.140491
resource representing a document's title	Distinct Characteristics and Complex Evolution of PEDV Strains, North America, May 2013–February 2014
has PubMed Central identifier	PMC4193278
has PubMed identifier	25279722
schema:publication	Emerg Infect Dis
resource representing a document's body	covid:351fca8e4bd7321d75ec0227794deb0db3567540#body_text
is schema:about of	named entity 'THESE' named entity 'S IN' named entity 'INDEL' named entity 'SPIKE' named entity 'DETERMINE' named entity 'GENE' named entity 'CLUSTERED' named entity 'HAVE' named entity 'IDENTITY' named entity 'ANALYZED' named entity '100%' named entity 'COMPLETE' named entity 'FORM' named entity 'COMPARED' covid:arg/351fca8e4bd7321d75ec0227794deb0db3567540 named entity 'OUR' named entity 'UNITED STATES' named entity 'SHARING' named entity 'ORIGINAL' named entity 'NORTH AMERICAN' named entity 'NORTH AMERICAN CLADE' named entity 'VIRULENT' named entity 'DISTINCT' named entity 'WORLDWIDE' named entity 'NORTH AMERICA' named entity 'IMPEDED' named entity 'PORCINE EPIDEMIC DIARRHEA VIRUS' named entity 'SPREAD' named entity 'SIMULTANEOUSLY' named entity 'INITIALLY' named entity 'GENOMES' named entity 'AVAILABILITY OF' named entity 'REPORTED' named entity 'INTRODUCED' named entity '28S' named entity 'GLOBAL' named entity 'INITIAL' named entity 'UNDERSTANDING' named entity 'CONTAINED' named entity 'INSERTIONS' named entity 'STRAINS' named entity 'OVERALL' named entity 'INTRODUCTION' named entity 'LIMITED' named entity 'RELATIONSHIP' named entity 'SHARE' named entity 'CLUSTER' named entity 'DEL' named entity 'STATES' named entity 'North America' named entity 'cluster' named entity 'clades' named entity 'deletions' named entity 'North America' named entity 'clade' named entity 'PEDV' named entity 'PEDV' named entity 'genome' named entity 'PEDV' named entity 'cdc' named entity 'PEDV' named entity 'PEDV' named entity 'North America' named entity 'genome replication' named entity 'open reading frames' named entity 'PEDV'

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