About: Viral Etiology of acute respiratory tract infections in hospitalized children and adults in Shandong Province, China

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About: Viral Etiology of acute respiratory tract infections in hospitalized children and adults in Shandong Province, China Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Viral Etiology of acute respiratory tract infections in hospitalized children and adults in Shandong Province, China
Creator	Xing, Chunyan Bi, Zhenqiang Lin, Yi Li, Zhong Guo, Nongjian Julong, Wu Liu, Ti Song, Shaoxia Wang, Xianjun Xu, Aiqiang Zhang, Shengyang
Source	Medline; PMC
abstract	BACKGROUND: The dominant viral etiologies responsible for acute respiratory infections (ARIs) are poorly understood, particularly among hospitalized patients. Improved etiological insight is needed to improve clinical management and prevention of ARIs. METHODS: Clinical and demographic information and throat swabs were collected from 607 patients from 2011 to 2013 in Shandong Province, China. Multiplex RT-PCR (SeeplexTM RV detection, Seegene) was performed to detected 12 respiratory viral pathogens. RESULTS: A total of 607 hospitalized patients were enrolled from 2011 to 2013. Viruses were identified in 35.75 % (217/607) of cases, including 78 influenza virus A and B (IVA and IVB), 47 para-influenza viruses (PIVs), 41 respiratory syncytial virus (RSV) and 38 adenovirus (ADV). For the children under 15 year old, the common detected viruses were influenza viruses, RSV, PIVS and ADV, while the principal respiratory viruses were human coronaviruses (HCoV), PIVs, influenza viruses for the old adults. Co-infections with multiple viruses were detected in 15.67 % of patients. Children under 5 years were more likely to have one or more detectable virus associated with their ARI. The peak of ARI caused by the respiratory viruses occurred in winter. CONCLUSION: This study demonstrated respiratory viruses were the major cause of hospitalized ARI patients in Shandong Province, influenza virus was the most common detected, RSV was the highest incidence among the young children (≤5 years). These findings also gave a better understand of virus distribution among different age and seasons, which help to consider potential therapeutic approaches and develop effective prevention strategies for respiratory virus infection.
has issue date	2015-10-14(xsd:dateTime)
bibo:doi	10.1186/s12985-015-0388-z
bibo:pmid	26467854
has license	cc-by
sha1sum (hex)	355eb5b5bf565e8e432d8746982b5100764db289
schema:url	https://doi.org/10.1186/s12985-015-0388-z
resource representing a document's title	Viral Etiology of acute respiratory tract infections in hospitalized children and adults in Shandong Province, China
has PubMed Central identifier	PMC4606902
has PubMed identifier	26467854
schema:publication	Virol J
resource representing a document's body	covid:355eb5b5bf565e8e432d8746982b5100764db289#body_text
is schema:about of	named entity 'respiratory tract infections' named entity 'adults' covid:arg/355eb5b5bf565e8e432d8746982b5100764db289 named entity 'UNDERSTOOD' named entity 'INSIGHT' named entity 'NEEDED' named entity 'ACUTE RESPIRATORY INFECTIONS' named entity 'HOSPITALIZED PATIENTS' named entity 'CLINICAL MANAGEMENT' named entity 'CHINA' named entity 'RESPIRATORY TRACT INFECTIONS' named entity 'RESPONSIBLE' named entity 'DOMINANT' named entity 'POORLY' named entity 'PREVENTION OF' named entity 'ACUTE' named entity 'ETIOLOGY' named entity 'VIRAL' named entity 'ADULTS' named entity 'VIRAL' named entity 'IMPROVED' named entity 'ETIOLOGIES' named entity 'HOSPITALIZED CHILDREN' named entity 'SHANDONG PROVINCE' named entity 'prevention' named entity 'ARIs' named entity 'needed' named entity 'Etiology' named entity 'ARIs' named entity 'etiology' named entity 'etiology' named entity 'Jinan' named entity 'co-infected' named entity 'body temperature' named entity 'influenza viruses' named entity 'statistically significant' named entity 'transient population' named entity 'seasonality' named entity 'chi-squared test' named entity 'H1N1' named entity 'study population' named entity 'respiratory symptoms' named entity 'ARIs' named entity 'viruses' named entity 'HRV' named entity 'deaths among children' named entity 'NL63' named entity 'ARIs' named entity 'young children' named entity 'pediatric' named entity 'sore throat' named entity 'antibiotics' named entity 'HRV' named entity 'pathogens' named entity 'viruses' named entity 'influenza virus' named entity 'Shenzhen' named entity 'Hong Kong' named entity 'influenza virus' named entity 'RSV' named entity 'viruses' named entity 'acute respiratory infections' named entity 'hMPV' named entity 'World Health Organization' named entity 'viruses' named entity 'cDNA' named entity 'infection' named entity 'ARIs' named entity 'pathogen' named entity 'ARIs' named entity 'socioeconomic'

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