About: Association of human leukocyte antigen class II alleles with severe acute respiratory syndrome in the Vietnamese population

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Association of human leukocyte antigen class II alleles with severe acute respiratory syndrome in the Vietnamese population
Creator	Hijikata, Minako Keicho, Naoto Itoyama, Satoru Quy, Tran Sasazuki, Takehiko Kashiwase, Koichi Sakurada, Shinsaku Satake, Masahiro Tokunaga, Katsushi Dang Ha, Le Khanh Hoa, Bach Le Hang, Long, Hoang Nguyen, Thi Phi, Nguyen Van Ban, Vo
source	Elsevier; Medline; PMC
abstract	Abstract Excessive immune response is believed to play a role in the development of severe acute respiratory syndrome (SARS). Inhomogeneous spread of SARS led one to think of an Asian genetic predisposition and contribution of human leukocyte antigen (HLA) to the disease susceptibility. However, past case-control studies showed inconsistent results. In Viet Nam, of 62 patients with SARS, 44 participated in the present study together with 103 individuals who had contact with SARS patients and 50 without contact history. HLA-DRB112 was more frequently shown in SARS patients than in controls (corrected p = 0.042). HLA-DRB11202, the predominant allele in the Vietnamese population showed the strongest association with SARS in a dominant model (corrected p = 0.0065 and 0.0052, depending on the controls to be compared). Our results and accumulated data on HLA in the Asian populations would help in the understanding of associations with emerging infectious diseases.
has issue date	2009-07-31(xsd:dateTime)
bibo:doi	10.1016/j.humimm.2009.05.006
bibo:pmid	19445991
has license	els-covid
sha1sum (hex)	366bdfe6dbeb2e98728f6d2d649c1c3ef6fc98f9
schema:url	https://doi.org/10.1016/j.humimm.2009.05.006
resource representing a document's title	Association of human leukocyte antigen class II alleles with severe acute respiratory syndrome in the Vietnamese population
has PubMed Central identifier	PMC7132661
has PubMed identifier	19445991
schema:publication	Human Immunology
resource representing a document's body	covid:366bdfe6dbeb2e98728f6d2d649c1c3ef6fc98f9#body_text
is schema:about of	named entity 'alleles' named entity 'severe acute respiratory syndrome' named entity 'ASSOCIATION' named entity 'HUMAN LEUKOCYTE ANTIGEN' named entity 'CLASS II' named entity 'ALLELES' named entity 'VIETNAMESE' named entity 'SEVERE ACUTE RESPIRATORY SYNDROME' named entity 'POPULATION' named entity 'alleles' named entity 'Hanoi' named entity 'haplotype' named entity 'SARS' named entity 'avian influenza' named entity 'HLA class II' named entity 'southeast Asia' named entity 'alleles' named entity 'class II' named entity 'Viet Nam' named entity 'HLA-DRB1' named entity 'SARS' named entity 'oligonucleotide probes' named entity 'pathogens' named entity 'Hong Kong' named entity 'HLA' named entity 'tuberculosis' named entity 'epitopes' named entity 'Allele frequencies' named entity 'HLA' named entity 'HLA' named entity 'alleles' named entity 'Singapore' named entity 'SARS-CoV' named entity 'HLA' named entity 'HLA' named entity 'HLA' named entity 'antigens' named entity 'genome' named entity 'HIV' named entity 'Applied Biosystems' named entity 'HLA-DRB1' named entity 'general population' named entity 'SARS' named entity 'Japan' named entity 'DNA samples' named entity 'H5N1' named entity 'HLA-DRB1' named entity 'control subjects' named entity 'HLA-DRB1' named entity 'infection' named entity 'Mainland Chinese' named entity 'Asian' named entity 'Asian' named entity 'HLA' named entity 'SARS' named entity 'Asian' named entity 'locus' named entity 'SARS' named entity 'allele' named entity 'alleles' named entity 'SARS' named entity 'SARS' named entity 'informed consent' named entity 'HLA-DRB1' named entity 'SARS' named entity 'SARS'

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