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About:
Self-reported symptoms of covid-19 including symptoms most predictive of SARS-CoV-2 infection, are heritable
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schema:ScholarlyArticle
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type
Academic Article
research paper
schema:ScholarlyArticle
isDefinedBy
Covid-on-the-Web dataset
title
Self-reported symptoms of covid-19 including symptoms most predictive of SARS-CoV-2 infection, are heritable
Creator
Falchi, Mario
Freidin, Maxim
Mangino, Massimo
Menni, Cristina
Spector, Tim
Steves, Claire
Visconti, Alessia
Couvreur, Simon
Davies, Richard
Sudre, Carole
Ce Bowyer, Ruth
Hammond, Christopher
Le Roy, Caroline
Mk, Frances
source
MedRxiv
abstract
Susceptibility to infection such as SARS-CoV-2 may be influenced by host genotype. TwinsUK volunteers (n=2633) completing the C-19 Covid symptom tracker app allowed classical twin studies of covid-19 symptoms including predicted covid-19, a symptom-based algorithm predicting true infection derived in app users tested for SARS-CoV-2. We found heritability for fever = 41 (95% confidence intervals 12-70)%; anosmia 47 (27-67)%; delirium 49 (24-75)%; and predicted covid-19 gave heritability = 50 (29-70)%.
has issue date
2020-04-24
(
xsd:dateTime
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bibo:doi
10.1101/2020.04.22.20072124
has license
medrxiv
sha1sum (hex)
36a8093911f60da9feae8cd63fb34cd54c9184b1
schema:url
https://doi.org/10.1101/2020.04.22.20072124
resource representing a document's title
Self-reported symptoms of covid-19 including symptoms most predictive of SARS-CoV-2 infection, are heritable
resource representing a document's body
covid:36a8093911f60da9feae8cd63fb34cd54c9184b1#body_text
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schema:about
of
named entity 'infection'
named entity 'predicting'
named entity 'delirium'
named entity 'TESTED FOR'
named entity 'DERIVED'
named entity 'tracker'
named entity 'SARS-CoV-2'
named entity 'heritability'
named entity 'app'
named entity 'SARS-CoV'
named entity 'TwinsUK'
named entity 'SARS-CoV-2'
named entity 'symptom'
named entity 'delirium'
named entity 'SARS-CoV'
named entity 'covid-19'
named entity 'infection'
named entity 'anosmia'
named entity 'intensive care'
named entity 'linear combination'
named entity 'H1N1 infection'
named entity 'covid-19'
named entity 'preprint'
named entity 'stochastic'
named entity 'immune response'
named entity 'genetic factors'
named entity 'co-habiting'
named entity 'heritable'
named entity 'risk of death'
named entity 'symptom'
named entity 'monozygotic'
named entity 'Heritability'
named entity 'immune response'
named entity 'Infectious diseases'
named entity 'SARS-CoV-2'
named entity 'TNF-α'
named entity 'Symptomatic infection'
named entity 'phenotypes'
named entity 'non-specific'
named entity 'dizygotic'
named entity 'Public health'
named entity 'symptom'
named entity 'allergies'
named entity 'volunteer bias'
named entity 'health records'
named entity 'preprint'
named entity 'infection'
named entity 'SARS-CoV-2'
named entity 'genotype'
named entity 'fever'
named entity 'Ethics committee'
named entity 'Heritability'
named entity 'anosmia'
named entity 'SARS-CoV-2 pandemic'
named entity 'Viral infections'
named entity 'TwinsUK'
named entity 'heritability'
named entity 'IL-1'
named entity 'liability threshold model'
named entity 'genetic basis'
named entity 'infection status'
named entity 'seasonal flu'
named entity 'TwinsUK'
named entity 'covid-19'
named entity 'genetic factors'
named entity 'persistent cough'
named entity 'phenotype'
named entity 'immune response'
named entity 'fever'
named entity 'medRxiv'
named entity 'body mass index'
named entity 'St Thomas' Hospital'
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