About: SARS: clinical features and diagnosis

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	SARS: clinical features and diagnosis
Creator	Wang, Chen Hui, David, Shu-Cheong Wong, Poon-Chuen
Source	Medline; PMC
abstract	Severe acute respiratory syndrome (SARS) is a highly infectious disease with a significant morbidity and case fatality. The major clinical features include persistent fever, chills/rigor, myalgia, malaise, dry cough, headache and dyspnoea. Less common symptoms include sputum production, sore throat, coryza, dizziness, nausea, vomiting and diarrhoea. Older subjects may present with decrease in general well‐being, poor feeding, fall/fracture and delirium, without the typical febrile response. Common laboratory features include lymphopenia with depletion of CD4 and CD8 lymphocytes, thrombocytopenia, prolonged activated partial thromboplastin time, elevated D‐Dimer, elevated alanine transminases, lactate dehydrogenase and creatinine kinase. The constellation of compatible clinical and laboratory findings, together with the rather characteristic radiological features especially on HRCT and the lack of clinical response to broad‐spectrum antibiotics, should quickly arouse suspicion of SARS. The positivity rates of urine, nasophargyngeal aspirate and stool specimen have been reported to be 42%, 68% and 97%, respectively, on day 14 of illness, whereas serology for confirmation may take 28 days to reach a detection rate above 90%. Recently, quantitative measurement of blood SARS CoV RNA with real‐time RT‐PCR technique has been developed with a detection rate of 80% as early as day 1 of hospital admission but the detection rates drop to 75% and 42% on day 7 and day 14, respectively.
has issue date	2003-11-14(xsd:dateTime)
bibo:doi	10.1046/j.1440-1843.2003.00520.x
bibo:pmid	15018129
has license	no-cc
sha1sum (hex)	37e3cfbdecf106b0da9e00404c1b26a879bb5cdc
schema:url	https://doi.org/10.1046/j.1440-1843.2003.00520.x
resource representing a document's title	SARS: clinical features and diagnosis
has PubMed Central identifier	PMC7169175
has PubMed identifier	15018129
schema:publication	Respirology
resource representing a document's body	covid:37e3cfbdecf106b0da9e00404c1b26a879bb5cdc#body_text
is schema:about of	named entity 'common' named entity 'features' named entity 'symptoms' named entity 'CORYZA' named entity 'INFECTIOUS DISEASE' named entity 'SUBJECTS' named entity 'LACK' named entity 'FEATURES' named entity 'CLINICAL RESPONSE' named entity 'CHILLS' named entity 'DIZZINESS' named entity 'ELEVATED D-DIMER' named entity 'RESPONSE TO' named entity 'elevated' named entity 'Less' named entity 'features' named entity 'coryza' named entity 'response' named entity 'features' named entity 'activated partial thromboplastin time' named entity 'febrile' named entity 'Severe acute respiratory syndrome (SARS)' named entity 'morbidity' named entity 'suspicion' named entity 'creatinine kinase' named entity 'delirium' named entity 'lactate dehydrogenase' named entity 'constellation' named entity 'diarrhoea' named entity 'D-Dimer' named entity 'SARS' named entity 'thrombocytopenia' named entity 'activated partial thromboplastin time' named entity 'lymphocytes' named entity 'CD4' named entity 'dyspnoea' named entity 'morbidity' named entity 'infectious disease' named entity 'coryza' named entity 'dizziness' named entity 'malaise' named entity 'SARS' named entity 'response' named entity 'symptom' named entity 'WHO' named entity 'SARS CoV' named entity 'SARS' named entity 'radiographic' named entity 'RNA' named entity 'SARS-CoV' named entity 'PCR' named entity 'epidemiologic' named entity 'CDC' named entity 'serum' named entity 'serology' named entity 'pneumonia' named entity 'RDS' named entity 'respiratory distress syndrome' named entity 'autopsy' named entity 'symptom' named entity 'oxygen desaturation' named entity 'acute respiratory distress syndrome' named entity 'delirium' named entity 'clinical features' named entity 'viral replication' named entity 'reverse transcriptase polymerase chain reaction' named entity 'bacterial pneumonia' named entity 'polymerase chain reaction' named entity 'epidemic' named entity 'coryza' named entity 'epidemiologic' named entity 'SARS CoV' named entity 'prognostic' named entity 'pneumonia' named entity 'HRCT' named entity 'SARS CoV' named entity '21 days' named entity 'local transmission'

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