About: Challenges, Learning Curve, and Safety of Endoscopic Endonasal Surgery of Sellar-Suprasellar Lesions in a Community Hospital

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About: Challenges, Learning Curve, and Safety of Endoscopic Endonasal Surgery of Sellar-Suprasellar Lesions in a Community Hospital Goto Sponge NotDistinct Permalink

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Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Challenges, Learning Curve, and Safety of Endoscopic Endonasal Surgery of Sellar-Suprasellar Lesions in a Community Hospital
Creator	Alkhamees, Abdullah Dang, Tommy Eaton, Sydney Elashaal, Abdurrahim Elbreki, Mustafa Haberfellner, Erika Im, Jacob Ling, Francis Morassutti, Dante Quint, Elise Shahab, Saba Shamisa, Abdalla Soliman, Mohamed O'connor, Avalon
Source	Elsevier; Medline; PMC
abstract	BACKGROUND AND OBJECTIVE: Endoscopic endonasal surgery (EES) for the management of sellar, suprasellar, and anterior skull base lesions is gaining popularity. Our aim was to analyze and present the clinical outcomes of EES for the management of these lesions in a community hospital setting. METHODS: We retrospectively reviewed the charts of 56 patients with sellar, suprasellar, and anterior skull base lesions who underwent EES between 2010 and 2018. RESULTS: There was male predominance (53.6%) with a mean age of 54.9 ± 13.7 years. Lesions were 45 pituitary adenomas, 5 meningiomas, 3 metastatic, 1 craniopharyngioma, 1 Rathke cyst, and 1 mucocele. Gross total excision was achieved in 57.1%, subtotal excision occurred in 37.5%, and decompression and biopsy were achieved in 5.4% patients. Postoperative vision normalized or improved in 27 patients (86.1%) and was stable in 4 patients (13.9%). Recovery of a preexisting hormonal deficit occurred in 13 (23.2%) patients, and a new hormonal deficit occurred in 9 patients (16.1%). The mean hospital stay was 6.1 ± 4.9 days. Postoperative complications included cerebrospinal fluid leak in 8 patients (14.3%). Four patients (7.1%) had meningitis. Diabetes insipidus was present in 19 patients (33.9%), and postoperative intracranial hematoma requiring evacuation was necessary in 2 patients (3.6%). The mean follow-up duration was 47.5 ± 25.8 months. Lesion progression or recurrence requiring redo surgery occurred in 5 patients (8.9%). Regarding the learning curve, the postoperative cerebrospinal fluid leak, meningitis, new hormonal deficits, and diabetes insipidus decreased in the second half of the patients. CONCLUSIONS: EES provides an effective and safe surgical option with low morbidity and mortality for the treatment of sellar, suprasellar, and anterior skull base lesions in a community hospital setting.
has issue date	2020-04-13(xsd:dateTime)
bibo:doi	10.1016/j.wneu.2020.04.028
bibo:pmid	32298827
has license	no-cc
sha1sum (hex)	38cc7da53dccb61a59cffcb5613aeead9d74de36
schema:url	https://doi.org/10.1016/j.wneu.2020.04.028
resource representing a document's title	Challenges, Learning Curve, and Safety of Endoscopic Endonasal Surgery of Sellar-Suprasellar Lesions in a Community Hospital
has PubMed Central identifier	PMC7195030
has PubMed identifier	32298827
schema:publication	World Neurosurg
resource representing a document's body	covid:38cc7da53dccb61a59cffcb5613aeead9d74de36#body_text
is schema:about of	named entity 'management' named entity 'Learning Curve' named entity 'Community Hospital' named entity 'CLINICAL OUTCOMES' named entity 'SUPRASELLAR' covid:arg/38cc7da53dccb61a59cffcb5613aeead9d74de36 named entity 'skull base' named entity 'lesions' named entity 'Endoscopic Endonasal Surgery' named entity 'Baxter Healthcare' named entity 'CSF leak' named entity 'neurosurgery' named entity 'adrenocorticotropic hormone' named entity 'transsphenoidal' named entity 'learning curve' named entity 'skull base' named entity 'CSF leak' named entity 'observational study' named entity 'fat' named entity 'turbinates' named entity 'tumor' named entity 'transsphenoidal surgery' named entity 'statistical significance' named entity 'learning curve' named entity 'mucocele' named entity 'vascularized' named entity '21.4%' named entity 'radiotherapy' named entity 'tumor' named entity 'lateralized' named entity 'tuberculum sellae' named entity 'endoscopic' named entity 'inlay and onlay' named entity 'pathology' named entity 'statistically significant' named entity 'Somerville, New Jersey' named entity 'gold standard' named entity 'neurosurgical' named entity 'skull base' named entity 'neurosurgeons' named entity 'Ethicon' named entity 'lumbar drain' named entity 'neurosurgeons' named entity 'transsphenoidal' named entity 'CSF leak' named entity 'hematoma' named entity 'hematomas' named entity 'hormonal' named entity 'endoscopic' named entity 'skull base' named entity 'evidence-based' named entity 'fascia lata' named entity 'suprasellar' named entity 'cranial nerve' named entity 'neurosurgeon' named entity 'tumor' named entity 'suprasellar' named entity 'diabetes insipidus' named entity 'olfactory groove' named entity 'meningitis' named entity 'COVID-19 pandemic' named entity 'anterior cranial fossa' named entity 'olfactory groove' named entity 'patient care' named entity 'Baxter Healthcare' named entity 'neurosurgeons' named entity 'endocrine' named entity 'hormonal'

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