About: Evaluation of an in-practice test for feline coronavirus antibodies

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Evaluation of an in-practice test for feline coronavirus antibodies
Creator	Golder, Matthew Jarrett, Oswald Ramsey, Ian Addie, Diane Mclachlan, Shona
topic	covid:3a16486a83cdb5e7d03a39f376219a97591eaadc#this
Source	Elsevier; Medline; PMC
abstract	Abstract A commercially available in-practice test for feline coronavirus (FCoV) antibodies (FCoV Immunocomb, Biogal Galed Laboratories) was evaluated by comparison with the gold standard FCoV immunofluorescent antibody (IFA) test. One hundred and three serum or plasma samples were selected and tested: 70 were positive by both tests, 24 were negative by both tests. The in-practice test produced five false positive and four false negative results. The sensitivity of the in-practice test was 95% and the specificity was 83%. When the titres were compared it was found that the in-practice test results were significantly correlated with IFA titres but the degree of correlation was not likely to be clinically useful. The IFA titres of the four false negative samples were found to be low (less than 40) which suggests that even a cat with a false negative result is still unlikely to be excreting FCoV. A negative result with the in-practice assay is likely to be reliable for screening cats prior to entry into an FCoV-free cattery or stud. It would also be useful in the investigation of suspected FIP as most cats with this condition have high IFA titres of antibodies. A strong positive result would be useful in the diagnosis of FIP (in conjunction with other biochemical and cytological testing), but positive results would be of limited value in monitoring FCoV infection in healthy cats as the antibody titre could not be reliably compared with those obtained with IFA. All positive results obtained using the in-practice kit should be confirmed and titrated by IFA. The kit also appeared to work efficiently with ascites samples (n=6) but too few samples were analysed to draw firm conclusions.
has issue date	2004-04-30(xsd:dateTime)
bibo:doi	10.1016/j.jfms.2004.01.001
bibo:pmid	15123150
has license	els-covid
sha1sum (hex)	3a16486a83cdb5e7d03a39f376219a97591eaadc
schema:url	https://doi.org/10.1016/j.jfms.2004.01.001
resource representing a document's title	Evaluation of an in-practice test for feline coronavirus antibodies
has PubMed Central identifier	PMC7128989
has PubMed identifier	15123150
schema:publication	Journal of Feline Medicine & Surgery
resource representing a document's body	covid:3a16486a83cdb5e7d03a39f376219a97591eaadc#body_text
is http://vocab.deri.ie/void#inDataset of	proxy:http/ns.inria.fr/covid19/3a16486a83cdb5e7d03a39f376219a97591eaadc
is schema:about of	named entity 'positive' named entity 'excreting' named entity 'IFA' named entity 'sensitivity' named entity 'samples' named entity 'EXCRETING' named entity 'PRACTICE' named entity 'CORRELATION' named entity 'NEGATIVE RESULTS' named entity 'TESTS' covid:arg/3a16486a83cdb5e7d03a39f376219a97591eaadc named entity 'FELINE CORONAVIRUS' named entity 'LOW' named entity 'IMMUNOFLUORESCENT' named entity 'FALSE NEGATIVE RESULT' named entity 'FOUND' named entity 'TEST' named entity 'CAT' named entity 'ANTIBODIES' named entity 'TEST' named entity 'PRACTICE' named entity 'NEGATIVE' named entity 'ONE HUNDRED' named entity 'ANTIBODY' named entity 'ANTIBODIES' named entity 'EVALUATION' named entity 'TEST RESULTS' named entity 'IFA' named entity 'AVAILABLE' named entity 'SERUM OR PLASMA' named entity 'GOLD STANDARD' named entity 'USEFUL' named entity 'UNLIKELY' named entity 'LABORATORIES' named entity 'FELINE CORONAVIRUS' named entity 'LIKELY' named entity 'SAMPLES' named entity 'SELECTED' named entity 'COMPARISON' named entity '40%' named entity 'SENSITIVITY' named entity 'POSITIVE' named entity 'CORRELATED' named entity 'EVALUATED' named entity 'FALSE POSITIVE' named entity 'SPECIFICITY' named entity 'DEGREE' named entity 'BUT' named entity 'FALSE NEGATIVE' named entity 'glycoprotein' named entity 'correlation' named entity 'non-specific' named entity 'result' named entity 'tests' named entity 'correlation' named entity 'FCoV' named entity 'FCoV' named entity 'seropositive' named entity 'antibody testing' named entity 'One' named entity 'titres' named entity 'correlation' named entity 'evaluated' named entity 'IFA test' named entity 'RT-PCR' named entity 'FCoV' named entity 'FIP' named entity 'seropositive' named entity 'antibodies' named entity 'serological tests' named entity 'room temperature' named entity 'antibody' named entity 'seronegative' named entity 'virus shedding' named entity 'antibodies'

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