About: Angiotensin converting enzyme: A review on expression profile and its association with human disorders with special focus on SARS-CoV-2 infection

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About: Angiotensin converting enzyme: A review on expression profile and its association with human disorders with special focus on SARS-CoV-2 infection Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Angiotensin converting enzyme: A review on expression profile and its association with human disorders with special focus on SARS-CoV-2 infection
Creator	Pyrc, Krzysztof Sanak, Marek Branicki, Wojciech Ghafouri-Fard, Soudeh Noroozi, Rezvan Pośpiech, Ewelina Taheri, Mohammad Vafaee, Reza Omrani, Davood Davood Omrani, Mir Sayad, Arezou
source	Elsevier; Medline; PMC
abstract	Angiotensin-converting enzyme (ACE) and its homologue, ACE2, have been mostly associated with hypertensive disorder. However, recent pandemia of SARS-CoV-2 has put these proteins at the center of attention, as this virus has been shown to exploit ACE2 protein to enter cells. Clear difference in the response of affected patients to this virus has urged researchers to find the molecular basis and pathophysiology of the cell response to this virus. Different levels of expression and function of ACE proteins, underlying disorders, consumption of certain medications and the existence of certain genomic variants within ACE genes are possible explanations for the observed difference in the response of individuals to the SARS-CoV-2 infection. In the current review, we discuss the putative mechanisms for this observation.
has issue date	2020-05-11(xsd:dateTime)
bibo:doi	10.1016/j.vph.2020.106680
bibo:pmid	32423553
has license	no-cc
sha1sum (hex)	3a6f155a213f44260bbfed4355d5e67f5f40ec1d
schema:url	https://doi.org/10.1016/j.vph.2020.106680
resource representing a document's title	Angiotensin converting enzyme: A review on expression profile and its association with human disorders with special focus on SARS-CoV-2 infection
has PubMed Central identifier	PMC7211701
has PubMed identifier	32423553
schema:publication	Vascul Pharmacol
resource representing a document's body	covid:3a6f155a213f44260bbfed4355d5e67f5f40ec1d#body_text
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