About: Emerging roles of deubiquitinases in cancer‐associated pathways

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About: Emerging roles of deubiquitinases in cancer‐associated pathways Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Emerging roles of deubiquitinases in cancer‐associated pathways
Creator	Clague, Michael Coulson, Judy Sacco, Joseph Urbé, Sylvie
source	Medline; PMC
abstract	Deubiquitinases (DUBs) are emerging as important regulators of many pathways germane to cancer. They may regulate the stability of key oncogenes, exemplified by USP28 stabilisation of c‐Myc. Alternatively they can negatively regulate ubiquitin‐dependent signalling cascades such as the NF‐κB activation pathway. We review the current literature that associates DUBs with cancer and discuss their suitability as drug targets of the future. © 2010 IUBMB IUBMB Life, 62(2): 140–157, 2010
has issue date	2010-01-13(xsd:dateTime)
bibo:doi	10.1002/iub.300
bibo:pmid	20073038
has license	no-cc
sha1sum (hex)	3c69e24e7dbabec4dedf6bc5932b0a1bcf6ff550
schema:url	https://doi.org/10.1002/iub.300
resource representing a document's title	Emerging roles of deubiquitinases in cancer‐associated pathways
has PubMed Central identifier	PMC7165618
has PubMed identifier	20073038
schema:publication	IUBMB Life
resource representing a document's body	covid:3c69e24e7dbabec4dedf6bc5932b0a1bcf6ff550#body_text
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