About: Clinical Characteristics of Diabetic Patients with COVID-19

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Clinical Characteristics of Diabetic Patients with COVID-19
Creator	Xiong, Nian Li, Fang Feng, Jiali Li, Guozhen Deng, Qin He, Qiong Southerland, Janet
Source	Medline; PMC
abstract	BACKGROUND: Since December 2019, novel coronavirus- (SARS-CoV-2) infected pneumonia (COVID-19) has rapidly spread throughout China. This study is aimed at describing the characteristics of COVID-19 patients in Wuhan. METHODS: 199 COVID-19 patients were admitted to Wuhan Red Cross Hospital in China from January 24th to March 15th. The cases were divided into diabetic and nondiabetic groups according to the history of taking antidiabetic drugs or by plasma fasting blood glucose level at admission, and the difference between groups were compared. RESULTS: Among 199 COVID-19 patients, 76 were diabetic and 123 were nondiabetic. Compared with nondiabetics, patients with diabetes had an older age, high levels of fasting plasma glucose (FPG), D-dimer, white blood cell, blood urea nitrogen (BUN) and total bilirubin (TBIL), lower levels of lymphocyte, albumin and oxygen saturation (SaO(2)), and higher mortality (P < 0.05). The two groups showed no difference in clinical symptoms. Diabetes, higher level of D-dimer at admission, and lymphocyte count less than 0.6 × 10(9)/L at admission were associated with increasing odds of death. Antidiabetic drugs were associated with decreasing odds of death. Treatment with low molecular weight heparin was not related to odds of death. CONCLUSION: The mortality rate of COVID-19 patients with diabetes was significantly higher than those without diabetes. Diabetes, higher level of D-dimer, and lymphocyte count less than 0.6 × 10(9)/L at admission were the risk factors associated with in-hospital death.
has issue date	2020-07-16(xsd:dateTime)
bibo:doi	10.1155/2020/1652403
bibo:pmid	32851093
has license	cc-by
sha1sum (hex)	3c82cf7a0072485cc0099c0866c23d2fbc53511f
schema:url	https://doi.org/10.1155/2020/1652403
resource representing a document's title	Clinical Characteristics of Diabetic Patients with COVID-19
has PubMed Central identifier	PMC7436283
has PubMed identifier	32851093
schema:publication	J Diabetes Res
resource representing a document's body	covid:3c82cf7a0072485cc0099c0866c23d2fbc53511f#body_text
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