About: Coronavirus Disease-2019 (COVID-19) Infection in a 3-Month-Old Infant: Clinical Features, Treatment and Probable Route of Transmission

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About: Coronavirus Disease-2019 (COVID-19) Infection in a 3-Month-Old Infant: Clinical Features, Treatment and Probable Route of Transmission Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Coronavirus Disease-2019 (COVID-19) Infection in a 3-Month-Old Infant: Clinical Features, Treatment and Probable Route of Transmission
Creator	Zhang, Lin Yuan, Jun Zhang, Xiao Shi, Jie Wang, Dahu Xie, Chaojun Dahu, Wang Jun, Yuan Liu, Xuexing Wei, Yuehong Xuexing, Liu Yuehong, Wei
Source	Elsevier; PMC
abstract	This study aims to explore the clinical and epidemiological characteristics of infant patients with coronavirus disease-2019 (COVID-19) infection. Clinical and epidemiological data of a 3-month-old patient with COVID-19 were collected, including general status, clinical results, laboratory tests, imaging characteristics, and epidemiological reports. The infant had no fever but had mild respiratory symptoms. The major laboratory results included normal white blood cell counts and lymphocytopenia, notably with elevated interleukin (IL-)-17A, IL-17 F, and tumor necrosis factor (TNF-)-α. The main manifestation of his chest computed tomography scan was pulmonary patchy shadows. All throat swabs and urine of the infant detected via Real-time Quantitative Polymerase Chain Reaction (RT-PCR) were negative, but his anal swab continued to test positive up to 40 days after onset of illness. Our study indicated that infants infected with COVID-19 may have relatively mild symptoms or clinical signs, IL-17A, IL-17 F, and TNF-α could be involved in the immune response of COVID-19. In addition, severe acute respiratory syndrome coronavirus 2(SARS-CoV-2) may shed through the gastrointestinal tract and convalescent carriers may exist among infant patients. We cannot rule out the possibility that infants may acquire infection from breastfeeding. Intensive care and nutrition support are recommended for infant patients with mild symptoms.
has issue date	2020-08-22(xsd:dateTime)
bibo:doi	10.1016/j.idcr.2020.e00937
has license	no-cc
sha1sum (hex)	3c8b81c502242e74dbb3421abbbf9c78b95b0565
schema:url	https://doi.org/10.1016/j.idcr.2020.e00937
resource representing a document's title	Coronavirus Disease-2019 (COVID-19) Infection in a 3-Month-Old Infant: Clinical Features, Treatment and Probable Route of Transmission
has PubMed Central identifier	PMC7443163
schema:publication	IDCases
resource representing a document's body	covid:3c8b81c502242e74dbb3421abbbf9c78b95b0565#body_text
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