About: Age-specific contacts and travel patterns in the spatial spread of 2009 H1N1 influenza pandemic

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Age-specific contacts and travel patterns in the spatial spread of 2009 H1N1 influenza pandemic Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Age-specific contacts and travel patterns in the spatial spread of 2009 H1N1 influenza pandemic
Creator	Colizza, Vittoria Poletto, Chiara Apolloni, Andrea
source	ArXiv; Medline; PMC
abstract	BACKGROUND: Confirmed H1N1 cases during late spring and summer 2009 in various countries showed a substantial age shift between importations and local transmission cases, with adults mainly responsible for seeding unaffected regions and children most frequently driving community outbreaks. METHODS: We introduce a multi-host stochastic metapopulation model with two age classes to analytically investigate the role of a heterogeneously mixing population and its associated non-homogeneous travel behaviors on the risk of a major epidemic. We inform the model with demographic data, contact data and travel statistics of Europe and Mexico, and calibrate it to the 2009 H1N1 pandemic early outbreak. We allow for variations of the model parameters to explore the conditions of invasion under different scenarios. RESULTS: We derive the expression for the potential of global invasion of the epidemic that depends on the transmissibility of the pathogen, the transportation network and mobility features, the demographic profile and the mixing pattern. Higher assortativity in the contact pattern greatly increases the probability of spatial containment of the epidemic, this effect being contrasted by an increase in the social activity of adults vs. children. Heterogeneous features of the mobility network characterizing its topology and traffic flows strongly favor the invasion of the pathogen at the spatial level, as also a larger fraction of children traveling. Variations in the demographic profile and mixing habits across countries lead to heterogeneous outbreak situations. Model results are compatible with the H1N1 spatial transmission dynamics observed. CONCLUSIONS: This work illustrates the importance of considering age-dependent mixing profiles and mobility features coupled together to study the conditions for the spatial invasion of an emerging influenza pandemic. Its results allow the immediate assessment of the risk of a major epidemic for a specific scenario upon availability of data, and the evaluation of the potential effectiveness of public health interventions targeting specific age groups, their interactions and mobility behaviors. The approach provides a general modeling framework that can be used for other types of partitions of the host population and applied to different settings.
has issue date	2013-04-15(xsd:dateTime)
bibo:doi	10.1186/1471-2334-13-176
bibo:pmid	23587010
has license	cc-by
sha1sum (hex)	3d3298c2222eff022ea013c3a58153f46bba6d02
schema:url	https://doi.org/10.1186/1471-2334-13-176
resource representing a document's title	Age-specific contacts and travel patterns in the spatial spread of 2009 H1N1 influenza pandemic
has PubMed Central identifier	PMC3644502
has PubMed identifier	23587010
schema:publication	BMC Infect Dis
resource representing a document's body	covid:3d3298c2222eff022ea013c3a58153f46bba6d02#body_text
is schema:about of	named entity '2009' named entity 'adults' named entity 'H1N1' named entity 'local transmission' named entity 'infectious diseases' named entity 'international alert' named entity 'Europe' named entity 'Italy' named entity 'assortativity' named entity 'metapopulation' named entity 'Poland' named entity 'epidemic' named entity 'antiviral treatment' named entity 'assortativity' named entity 'empirical evidence' named entity 'asymptomatic infections' named entity 'emerging pathogen' named entity 'influenza' named entity 'diffusion' named entity 'epidemic spread' named entity 'travel behavior' named entity 'agent-based' named entity 'exponentially distributed' named entity 'metapopulation' named entity 'H1N1 pandemic' named entity 'epidemic' named entity 'epidemic' named entity 'Mexico' named entity '2009 H1N1 pandemic' named entity 'reproductive number' named entity 'probability' named entity 'heterogeneities' named entity 'H1N1' named entity 'population model' named entity 'assortativity' named entity 'local transmission' named entity 'assortativity' named entity 'demographic data' named entity 'risk assessment' named entity 'probability' named entity 'social activity' named entity 'Mexico' named entity 'demographic features' named entity 'probability' named entity '2009 H1N1 pandemic' named entity 'epidemic' named entity 'H1N1 pandemic' named entity 'probability' named entity 'epidemics' named entity 'travel behavior' named entity 'travel behavior' named entity 'reproductive number' named entity 'travel behavior' named entity 'reproductive number' named entity 'empirical findings' named entity 'travel behavior' named entity 'demographic' named entity 'per-capita' named entity 'Belgium' named entity 'metapopulation' named entity 'assortativity' named entity '2009 H1N1 pandemic' named entity 'epidemic spread' named entity 'diffusion rate' named entity 'transmission rate' named entity 'Mexico' named entity 'latency period' named entity 'vaccination' named entity 'travel behavior' named entity 'epidemic' named entity 'continental Europe' named entity 'epidemic' named entity 'epidemic' named entity 'epidemic' named entity 'H1N1 pandemic' named entity 'travel behavior' named entity 'epidemic' named entity 'epidemic' named entity 'dashed'

Faceted Search & Find service v1.13.91 as of Mar 24 2020

Alternative Linked Data Documents: Sponger | ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3229 as of Jul 10 2020, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (94 GB total memory)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2025 OpenLink Software