About: Diagnostic value of peripheral hematologic markers for coronavirus disease 2019 (COVID‐19): A multicenter, cross‐sectional study

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Diagnostic value of peripheral hematologic markers for coronavirus disease 2019 (COVID‐19): A multicenter, cross‐sectional study Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Diagnostic value of peripheral hematologic markers for coronavirus disease 2019 (COVID‐19): A multicenter, cross‐sectional study
Creator	Yuan, Guodan Feng, Longhua Peng, Junnan Wang, Daoxin Deng, \| Mei, Ying Qi, \|
Source	Medline; PMC
abstract	BACKGROUND: To determine the diagnostic value of hematologic markers for coronavirus disease 2019 (COVID‐19) and explore their relationship with disease severity. METHODS: Subjects included 190 COVID‐19 patients, 190 healthy subjects, and 105 influenza pneumonia (IP) patients. COVID‐19 patients were divided into the ARDS and non‐ARDS groups. Routine blood examination, biochemistry indicator, days in hospital, body temperature, pneumonia severity index (PSI), CURB‐65, and MuLBSTA were recorded. Correlations between variables were assessed using Spearman's correlation analysis. Receiver operating characteristic (ROC) curves were used to study the accuracy of the various diagnostic tests. RESULTS: Compared with healthy subjects, COVID‐19 patients had lower white blood cell (WBC), lymphocyte, platelet, and hemoglobin levels; higher percentages of neutrophils and monocytes; lower percentages of lymphocytes and higher neutrophil‐to‐lymphocyte ratio (NLR), monocyte‐to‐lymphocyte ratio (MLR), and platelet‐to‐lymphocyte ratio (PLR) values (P < .05). COVID‐19 patients had higher WBC and neutrophil levels and lower percentages of lymphocytes compared to IP (P < .05). ROC curve analysis revealed that MLR had a high diagnostic value in differentiating COVID‐19 patients from healthy subjects, but not from IP patients. NLR showed significant positive correlations with PSI, CURB‐65, and MuLBSTA. Lymphocyte count was lower in the ARDS group and yielded a higher diagnostic value than the other variables. CONCLUSIONS: Monocyte‐to‐lymphocyte ratio showed an acceptable efficiency to separate COVID‐19 patients from healthy subjects, but failed to rule out IP patients. NLR may be a reliable marker to evaluate the disease severity of COVID‐19. Lymphocyte count may be useful to establish the early diagnosis of ARDS in the COVID‐19 patients.
has issue date	2020-07-17(xsd:dateTime)
bibo:doi	10.1002/jcla.23475
bibo:pmid	32681559
has license	cc-by-nc-nd
sha1sum (hex)	3d9b54de9d687ff2202c1a456c6f3a4e70ae10f0
schema:url	https://doi.org/10.1002/jcla.23475
resource representing a document's title	Diagnostic value of peripheral hematologic markers for coronavirus disease 2019 (COVID‐19): A multicenter, cross‐sectional study
has PubMed Central identifier	PMC7404368
has PubMed identifier	32681559
schema:publication	J Clin Lab Anal
resource representing a document's body	covid:3d9b54de9d687ff2202c1a456c6f3a4e70ae10f0#body_text
is schema:about of	named entity 'PSI' named entity 'multicenter' named entity 'sectional' named entity 'indicator' named entity 'adaptations' named entity 'hematologic' named entity 'coronavirus disease 2019' named entity 'pneumonia' named entity 'hospital' named entity 'ROC' named entity 'pneumonia' named entity 'open access' named entity 'Receiver operating characteristic' named entity 'influenza' named entity 'biochemistry' named entity 'body temperature' named entity 'COVID' named entity 'C-reactive protein' named entity 'lymphocyte' named entity 'AST' named entity 'normal range' named entity 'CURB-65' named entity 'COVID-19' named entity 'isoenzyme' named entity 'lymphocyte' named entity 'ARDS' named entity 'PSI' named entity 'aspartate aminotransferase' named entity '0.51' named entity 'normal range' named entity 'erythrocyte sedimentation rate' named entity 'COVID-19' named entity 'medical history' named entity 'intensive care' named entity 'pneumonia severity index' named entity 'Hubei Province' named entity 'HGB' named entity 'pharyngeal' named entity '10.31' named entity 'case fatality rate' named entity 'hemoglobin' named entity 'isoenzyme' named entity 'normal range' named entity 'early diagnosis' named entity 'SARS' named entity 'lymphocytes' named entity 'Declaration of Helsinki' named entity 'neutrophil' named entity 'lymphocyte' named entity 'monocytes' named entity 'ARDS' named entity 'ARDS' named entity 'Lymphocyte count' named entity 'monocyte' named entity 'COVID' named entity 'COVID' named entity 'COVID' named entity 'COVID' named entity 'COVID' named entity 'COVID' named entity 'µmol/L' named entity 'COVID' named entity 'COVID-19' named entity 'C-reactive protein' named entity 'South Korea' named entity 'P 2' named entity 'ARDS' named entity 'monocyte' named entity 'neutrophil' named entity 'CRP' named entity 'ARDS' named entity 'monocytes' named entity 'selection bias' named entity 'erythrocyte sedimentation rate' named entity 'procalcitonin'

Faceted Search & Find service v1.13.91 as of Mar 24 2020

Alternative Linked Data Documents: Sponger | ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3229 as of Jul 10 2020, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (94 GB total memory)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2025 OpenLink Software