About: A Comparison of Mortality-related Risk Factors of COVID-19, SARS, and MERS: A Systematic Review and Meta-analysis

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About: A Comparison of Mortality-related Risk Factors of COVID-19, SARS, and MERS: A Systematic Review and Meta-analysis Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	A Comparison of Mortality-related Risk Factors of COVID-19, SARS, and MERS: A Systematic Review and Meta-analysis
Creator	Lin, Li Zhang, Xin Lin, Xi Liu, Jun Zhang, Ke Li, Zhiming Jiang, Lin, ; Zhang, ; Yang, ; Yang, Xingfen Bian, Ziwei Hu, Manjiang Huang, Yuji Huang, Zhenlie Jiang, Junying Junying, ; Liang, Boxuan Lu, Lvliang Zhong, Wenyu Zhong, Yizhou
Source	Elsevier; Medline; PMC
abstract	Objective: Coronavirus Disease 2019 (COVID-19) is a pandemic. This systematic review compares mortality risk factors including clinical, demographic and laboratory features of COVID-19, Severe Acute Respiratory Syndrome (SARS) and Middle East Respiratory Syndrome (MERS). The aim is to provide new strategies for COVID-19 prevention and treatment. Methods: We performed a systematic review with meta-analysis, using five databases to compare the predictors of death for COVID-19, SARS and MERS. A random-effects model meta-analysis calculated odds ratios (OR) and 95% confidence intervals (95% CI). Results: 845 articles up through 11/4/2020 were retrieved, but only 28 studies were included in this meta-analysis. The results showed that males had a higher likelihood of death than females (OR = 1.82, 95% CI 1.56-2.13). Age (OR = 7.86, 95% CI 5.46-11.29), diabetes comorbidity (OR = 3.73, 95% CI 2.35-5.90), chronic lung disease (OR = 3.43, 95% CI 1.80-6.52) and hypertension (OR = 3.38, 95% CI 2.45-4.67) were the mortality risk factors. The laboratory indicators lactic dehydrogenase (OR = 37.52, 95% CI 24.68-57.03), C-reactive protein (OR = 12.11, 95% CI 5.24-27.98), and neutrophils (OR = 17.56, 95% CI 10.67-28.90) had stronger correlations with COVID-19 mortality than with SARS or MERS mortality. Consolidation and ground-glass opacity imaging features were similar among COVID-19, SARS, and MERS patients. Conclusions: COVID-19’s mortality factors are similar to those of SARS and MERS. Age and laboratory indicators could be effective predictors of COVID-19 mortality outcomes.
has issue date	2020-07-04(xsd:dateTime)
bibo:doi	10.1016/j.jinf.2020.07.002
bibo:pmid	32634459
has license	no-cc
sha1sum (hex)	3e1fcb792dc3840b48e1d7e4f4920f07653bfde2
schema:url	https://doi.org/10.1016/j.jinf.2020.07.002
resource representing a document's title	A Comparison of Mortality-related Risk Factors of COVID-19, SARS, and MERS: A Systematic Review and Meta-analysis
has PubMed Central identifier	PMC7334925
has PubMed identifier	32634459
schema:publication	J Infect
resource representing a document's body	covid:3e1fcb792dc3840b48e1d7e4f4920f07653bfde2#body_text
is schema:about of	named entity 'patients' named entity 'COVID-19' named entity 'COVID-19' named entity 'MERS' named entity 'Review' named entity 'HIGHER' named entity 'CLINICAL' named entity 'FEATURES' named entity 'IMAGING' named entity 'FEMALES' named entity 'BUT' named entity 'META-ANALYSIS' named entity 'CORONAVIRUS DISEASE 2019' named entity 'DIABETES' named entity '10.67' named entity 'C-REACTIVE PROTEIN' named entity 'meta-analysis' named entity '95% CI' named entity 'calculated' named entity 'Results' named entity 'databases' named entity 'laboratory' named entity 'risk factors' named entity 'MERS' named entity 'COVID-19' named entity '95% CI' named entity 'neutrophils' named entity '11/4' named entity 'lactic dehydrogenase' named entity 'odds ratios' named entity 'comorbidity' named entity '2.35' named entity 'meta-analysis' named entity 'odds ratios' named entity 'COVID-19' named entity 'COVID' named entity 'COVID' named entity 'C-reactive protein' named entity 'hypertension' named entity 'SARS' named entity 'MERS' named entity 'systematic review' named entity 'meta-analysis' named entity 'SARS' named entity 'Systematic Review' named entity 'odds ratios' named entity 'odds ratios' named entity 'odds ratios' named entity '11/4' named entity 'chronic lung disease' named entity 'meta-analysis' named entity 'comorbidity' named entity 'systematic review' named entity 'meta-analysis' named entity 'SARS' named entity 'hypertension' named entity '95% CI' named entity 'odds ratios' named entity 'odds ratios' named entity 'odds ratios' named entity '95%'

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