About: Neonatal outcome in 29 pregnant women with COVID-19: A retrospective study in Wuhan, China

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Neonatal outcome in 29 pregnant women with COVID-19: A retrospective study in Wuhan, China Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Neonatal outcome in 29 pregnant women with COVID-19: A retrospective study in Wuhan, China
Creator	Yang, Jing Zhang, Chen Chen, Yang Liu, Jun Liu, Han Xu, Liu Chen, Yan-Fen Cheng, Bi-Heng Dennisid, Cindy-Lee Huangid, He-Feng Jiang, Ling Kawaiid, Andrew Liid, Cheng Molid, Ben Qian, Zhao-Xia Wangid, Yu Wu, Yan-Ting Xiong, Guo-Ping Xu, Jing-Jing Yang, Wen
Source	Medline; PMC
abstract	BACKGROUND: As of June 1, 2020, coronavirus disease 2019 (COVID-19) has caused more than 6,000,000 infected persons and 360,000 deaths globally. Previous studies revealed pregnant women with COVID-19 had similar clinical manifestations to nonpregnant women. However, little is known about the outcome of neonates born to infected women. METHODS AND FINDINGS: In this retrospective study, we studied 29 pregnant women with COVID-19 infection delivered in 2 designated general hospitals in Wuhan, China between January 30 and March 10, 2020, and 30 neonates (1 set of twins). Maternal demographic characteristics, delivery course, symptoms, and laboratory tests from hospital records were extracted. Neonates were hospitalized if they had symptoms (5 cases) or their guardians agreed to a hospitalized quarantine (13 cases), whereas symptom-free neonates also could be discharged after birth and followed up through telephone (12 cases). For hospitalized neonates, laboratory test results and chest X-ray or computed tomography (CT) were extracted from hospital records. The presence of antibody of SARS-CoV-2 was assessed in the serum of 4 neonates. Among 29 pregnant COVID-19-infected women (13 confirmed and 16 clinical diagnosed), the majority had higher education (56.6%), half were employed (51.7%), and their mean age was 29 years. Fourteen women experienced mild symptoms including fever (8), cough (9), shortness of breath (3), diarrhea (2), vomiting (1), and 15 were symptom-free. Eleven of 29 women had pregnancy complications, and 27 elected to have a cesarean section delivery. Of 30 neonates, 18 were admitted to Wuhan Children’s Hospital for quarantine and care, whereas the other 12 neonates discharged after birth without any symptoms and had normal follow-up. Five hospitalized neonates were diagnosed as COVID-19 infection (2 confirmed and 3 suspected). In addition, 12 of 13 other hospitalized neonates presented with radiological features for pneumonia through X-ray or CT screening, 1 with occasional cough and the others without associated symptoms. SARS-CoV-2 specific serum immunoglobulin M (IgM) and immunoglobulin G (IgG) were measured in 4 neonates and 2 were positive. The limited sample size limited statistical comparison between groups. CONCLUSIONS: In this study, we observed COVID-19 or radiological features of pneumonia in some, but not all, neonates born to women with COVID-19 infection. These findings suggest that intrauterine or intrapartum transmission is possible and warrants clinical caution and further investigation. TRIAL REGISTRATION: Chinese Clinical Trial Registry, ChiCTR2000031954 (Maternal and Perinatal Outcomes of Women with coronavirus disease 2019 (COVID-19): a multicenter retrospective cohort study).
has issue date	2020-07-28(xsd:dateTime)
bibo:doi	10.1371/journal.pmed.1003195
bibo:pmid	32722722
has license	cc-by
sha1sum (hex)	3e5d0063f8958c8c531981fbfc27ec0d3b697e27
schema:url	https://doi.org/10.1371/journal.pmed.1003195
resource representing a document's title	Neonatal outcome in 29 pregnant women with COVID-19: A retrospective study in Wuhan, China
has PubMed Central identifier	PMC7386573
has PubMed identifier	32722722
schema:publication	PLoS Med
resource representing a document's body	covid:3e5d0063f8958c8c531981fbfc27ec0d3b697e27#body_text
is schema:about of	named entity 'born' named entity 'infected' named entity 'ACCESS' named entity 'WOMEN' named entity 'PREGNANT WOMEN' named entity 'INFECTED' named entity 'DEATHS' named entity 'KNOWN' named entity 'SIMILAR' named entity 'June' named entity 'coronavirus disease 2019' named entity 'pregnant women' named entity 'RNA' named entity 'antenatal' named entity 'antenatal' named entity 'SARS-CoV-2' named entity 'amniotic fluid' named entity 'IgG' named entity 'hypoxic-ischemic encephalopathy' named entity 'neonates' named entity 'neonates' named entity 'Medical Ethical' named entity 'neonatal ICU' named entity 'inhalation' named entity 'NEC' named entity 'PCR' named entity 'neutrophil' named entity 'pneumatosis' named entity 'demographic characteristics' named entity 'fetal' named entity 'congenital heart disease' named entity 'fetus' named entity 'HBV' named entity 'jejunal' named entity 'COVID-19' named entity 'Huazhong University of Science and Technology' named entity 'SARS-CoV-2' named entity 'birthweight' named entity 'SARS-CoV-2' named entity 'SARS-CoV-2' named entity 'computed tomography' named entity 'Wuhan University' named entity 'lung' named entity 'IgM' named entity 'NEC' named entity 'placenta' named entity 'mainland China' named entity 'Public Health Emergency of International Concern' named entity 'pneumonia' named entity 'cesarean section' named entity 'general hospitals' named entity 'IgG' named entity 'chest CT' named entity 'IgG' named entity 'neonates' named entity 'risk factors' named entity 'interstitial fibrosis' named entity 'pneumonia' named entity 'follow-up' named entity 'patent ductus arteriosus' named entity 'respiratory tract' named entity 'neonates'

Faceted Search & Find service v1.13.91 as of Mar 24 2020

Alternative Linked Data Documents: Sponger | ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3229 as of Jul 10 2020, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (94 GB total memory)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software