About: Role of emerging respiratory viruses in children with severe acute wheezing

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Role of emerging respiratory viruses in children with severe acute wheezing
Creator	Calvo, C Casas, I García-García, M Pozo, F De Cea, J Pé Rez-Breñ, P Falcó, A
Source	Medline; PMC
abstract	BACKGROUND: Acute wheezing episodes are frequently associated with respiratory viral infections in children. However, the role of the recently described respiratory viruses is not yet fully understood. OBJECTIVE: The main objective of this study was to estimate the frequency of human metapneumovirus (HMPV), human bocavirus (HBoV), and 14 other respiratory viruses in hospitalized children with acute wheezing. METHODS: A prospective study was conducted on children <14 years old, admitted with an acute expiratory wheezing episode from September 2005 to June 2008. Viruses were detected in nasopharyngeal aspirates by polymerase chain reaction. Clinical data were prospectively recorded. RESULTS: A viral pathogen was identified in 444 (71%) out of 626 hospitalized acute wheezing episodes. Respiratory syncytial virus (RSV) was the most frequently detected (27%), followed by rhinovirus (24%), adenovirus (17.8%), HBoV (16%), and HMPV (4.7%). The rate of viral detection was significantly higher in infants (77.3%), than in older children (59.8%) (P < 0.001). RSV and HBoV were more prevalent in infants (P < 0.001) than in older children. CONCLUSION: The most prevalent viruses found in severe acute wheezing episodes were RSV and rhinovirus not only in childhood, but also in infancy. However, other emerging viruses such as HBoV and metapneumovirus also play an important role in wheezing episodes. Pediatr Pulmonol. 2010; 45:585–591. © 2010 Wiley‐Liss, Inc.
has issue date	2010-05-06(xsd:dateTime)
bibo:doi	10.1002/ppul.21225
bibo:pmid	20503284
has license	no-cc
sha1sum (hex)	3e84b45572f0f44905329b9cb7700d3bfcfc5779
schema:url	https://doi.org/10.1002/ppul.21225
resource representing a document's title	Role of emerging respiratory viruses in children with severe acute wheezing
has PubMed Central identifier	PMC7167793
has PubMed identifier	20503284
schema:publication	Pediatr Pulmonol
resource representing a document's body	covid:3e84b45572f0f44905329b9cb7700d3bfcfc5779#body_text
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