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About:
Characterization of Patients Who Return to Hospital Following Discharge from Hospitalization for COVID-19
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schema:ScholarlyArticle
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wasabi.inria.fr
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Type:
Academic Article
research paper
schema:ScholarlyArticle
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type
Academic Article
research paper
schema:ScholarlyArticle
isDefinedBy
Covid-on-the-Web dataset
has title
Characterization of Patients Who Return to Hospital Following Discharge from Hospitalization for COVID-19
Creator
Zhao, Shan
Fayad, Zahi
Fuster, Valentin
Glicksberg, Benjamin
Lala, Anuradha
Bottinger, Erwin
Charney, Alexander
De Freitas, Jessica
Just, Allan
Levin, Matthew
Nadkarni, Girish
Naik, Nidhi
Sigel, Keith
Somani, Sulaiman
Richter, Felix
Source
Medline; PMC
abstract
BACKGROUND: Data on patients with coronavirus disease 2019 (COVID-19) who return to hospital after discharge are scarce. Characterization of these patients may inform post-hospitalization care. OBJECTIVE: To describe clinical characteristics of patients with COVID-19 who returned to the emergency department (ED) or required readmission within 14 days of discharge. DESIGN: Retrospective cohort study of SARS-COV-2-positive patients with index hospitalization between February 27 and April 12, 2020, with ≥ 14-day follow-up. Significance was defined as P < 0.05 after multiplying P by 125 study-wide comparisons. PARTICIPANTS: Hospitalized patients with confirmed SARS-CoV-2 discharged alive from five New York City hospitals. MAIN MEASURES: Readmission or return to ED following discharge. RESULTS: Of 2864 discharged patients, 103 (3.6%) returned for emergency care after a median of 4.5 days, with 56 requiring inpatient readmission. The most common reason for return was respiratory distress (50%). Compared with patients who did not return, there were higher proportions of COPD (6.8% vs 2.9%) and hypertension (36% vs 22.1%) among those who returned. Patients who returned also had a shorter median length of stay (LOS) during index hospitalization (4.5 [2.9,9.1] vs 6.7 [3.5, 11.5] days; P(adjusted) = 0.006), and were less likely to have required intensive care on index hospitalization (5.8% vs 19%; P(adjusted) = 0.001). A trend towards association between absence of in-hospital treatment-dose anticoagulation on index admission and return to hospital was also observed (20.9% vs 30.9%, P(adjusted) = 0.06). On readmission, rates of intensive care and death were 5.8% and 3.6%, respectively. CONCLUSIONS: Return to hospital after admission for COVID-19 was infrequent within 14 days of discharge. The most common cause for return was respiratory distress. Patients who returned more likely had COPD and hypertension, shorter LOS on index-hospitalization, and lower rates of in-hospital treatment-dose anticoagulation. Future studies should focus on whether these comorbid conditions, longer LOS, and anticoagulation are associated with reduced readmissions. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1007/s11606-020-06120-6) contains supplementary material, which is available to authorized users.
has issue date
2020-08-19
(
xsd:dateTime
)
bibo:doi
10.1007/s11606-020-06120-6
bibo:pmid
32815060
has license
no-cc
sha1sum (hex)
3e89db2dba69160e7e6da01a761eac286871460d
schema:url
https://doi.org/10.1007/s11606-020-06120-6
resource representing a document's title
Characterization of Patients Who Return to Hospital Following Discharge from Hospitalization for COVID-19
has PubMed Central identifier
PMC7437962
has PubMed identifier
32815060
schema:publication
J Gen Intern Med
resource representing a document's body
covid:3e89db2dba69160e7e6da01a761eac286871460d#body_text
is
schema:about
of
named entity 'COVID-19'
named entity 'Hospitalization'
named entity 'COVID'
named entity 'Institutional Review Board'
named entity 'data hygiene'
named entity 'platelet counts'
named entity 'fibrinogen'
named entity 'anticoagulation'
named entity 'comorbidities'
named entity 'chi-squared'
named entity 'ICU'
named entity 'ICU'
named entity 'rivaroxaban'
named entity 'anticoagulation'
named entity '26.1'
named entity 'statistical power'
named entity 'clinical characteristics'
named entity 'COVID'
named entity 'COVID'
named entity 'Mount Sinai'
named entity 'erythrocyte sedimentation rate'
named entity 'edoxaban'
named entity 'SARS-COV-2'
named entity 'respiratory rate'
named entity 'COVID'
named entity 'measurement error'
named entity 'respiratory distress'
named entity 'CAD'
named entity 'statistically significant'
named entity 'reviparin'
named entity 'National Institutes of Health'
named entity 'hypertension'
named entity 'COVID'
named entity 'COPD'
named entity 'respiratory distress'
named entity 'coronavirus disease 2019'
named entity 'anticoagulation'
named entity 'BMI'
named entity 'enoxaparin'
named entity 'COVID-19 pandemic'
named entity 'basic metabolic panel'
named entity 'SARS-CoV-2'
named entity 'Mount Sinai'
named entity 'oxygen support'
named entity 'pneumonia'
named entity 'COVID'
named entity 'medical condition'
named entity 'BMI'
named entity 'ICU'
named entity 'BMI'
named entity 'ABG'
named entity 'hospital readmission'
named entity 'hypertension'
named entity 'EHR'
named entity 'anticoagulation'
named entity 'COVID'
named entity 'coronavirus disease 2019'
named entity 'non-invasive'
named entity 'respiratory distress'
named entity 'procalcitonin'
named entity 'apixaban'
named entity 'chronic kidney disease'
named entity 'CKD'
named entity 'low molecular weight heparin'
named entity 'continuous variable'
named entity 'chest pain'
named entity 'Retrospective cohort study'
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