About: The NIAID Integrated Research Facility at Frederick, Maryland: A unique international resource to facilitate medical countermeasure development for BSL-4 pathogens

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About: The NIAID Integrated Research Facility at Frederick, Maryland: A unique international resource to facilitate medical countermeasure development for BSL-4 pathogens Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	The NIAID Integrated Research Facility at Frederick, Maryland: A unique international resource to facilitate medical countermeasure development for BSL-4 pathogens
Creator	Kindrachuk, Jason Jahrling, Peter Johnson, Reed Bollinger, Laura Keith, Lauren Hensley, Lisa Kuhn, Jens Lackemeyer, Matthew Claire, Marisa
Source	Medline; PMC
abstract	Scientists at the National Institute of Allergy and Infectious Diseases Integrated Research Facility at Fort Detrick, Frederick, Maryland coordinate and facilitate preclinical research on infectious diseases to develop medical countermeasures for high consequence pathogens. This facility is unique in that it is the only maximum containment laboratory in the world where conventional and molecular medical imaging equipment are incorporated into the design of the facility. This capability provides investigators with unique tools to dissect disease pathogenesis, evaluate the ability of animal models to recapitulate human disease, and test candidate countermeasures. Importantly, advanced molecular imaging has the potential to provide alternative endpoints to lethality. By using these alternative endpoints, investigators can reduce the number of animals used in experiments and evaluate countermeasures in sublethal models. With the incorporation of medical imaging modalities, a clinical laboratory modeled after those existing in hospitals, and a highly trained veterinary medicine team, IRF Frederick is uniquely suited to advance our understanding of emerging infectious diseases and to facilitate the development of medical countermeasures and clinical care paradigms previously considered impossible.
has issue date	2014-05-08(xsd:dateTime)
bibo:doi	10.1111/2049-632x.12171
bibo:pmid	24687975
has license	bronze-oa
sha1sum (hex)	3f08d3c1f07751d8d55bf6a331b38ae652c7f833
schema:url	https://doi.org/10.1111/2049-632x.12171
resource representing a document's title	The NIAID Integrated Research Facility at Frederick, Maryland: A unique international resource to facilitate medical countermeasure development for BSL-4 pathogens
has PubMed Central identifier	PMC4106974
has PubMed identifier	24687975
schema:publication	Pathogens and Disease
resource representing a document's body	covid:3f08d3c1f07751d8d55bf6a331b38ae652c7f833#body_text
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