About: Phosphatidylserine receptors: Enhancers of enveloped virus entry and infection

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Phosphatidylserine receptors: Enhancers of enveloped virus entry and infection
Creator	Maury, Wendy Moller-Tank, Sven
Source	Elsevier; Medline; PMC
abstract	Abstract A variety of both RNA and DNA viruses envelop their capsids in a lipid bilayer. One of the more recently appreciated benefits this envelope is incorporation of phosphatidylserine (PtdSer). Surface exposure of PtdSer disguises viruses as apoptotic bodies; tricking cells into engulfing virions. This mechanism is termed apoptotic mimicry. Several PtdSer receptors have been identified to enhance virus entry and we have termed this group of proteins PtdSer-mediated virus entry enhancing receptors or PVEERs. These receptors enhance entry of a range of enveloped viruses. Internalization of virions by PVEERs provides a broad mechanism of entry with little investment by the virus itself. PVEERs may allow some viruses to attach to cells, thereby making viral glycoprotein/cellular receptor interactions more probable. Alternatively, other viruses may rely entirely on PVEERs for internalization into endosomes. This review provides an overview of PtdSer receptors that serve as PVEERs and the biology behind virion/PVEER interaction.
has issue date	2014-11-30(xsd:dateTime)
bibo:doi	10.1016/j.virol.2014.09.009
bibo:pmid	25277499
has license	els-covid
sha1sum (hex)	3f3a1bb0cbebc568b171a092ea078f790bf4f7fe
schema:url	https://doi.org/10.1016/j.virol.2014.09.009
resource representing a document's title	Phosphatidylserine receptors: Enhancers of enveloped virus entry and infection
has PubMed Central identifier	PMC4252826
has PubMed identifier	25277499
schema:publication	Virology
resource representing a document's body	covid:3f3a1bb0cbebc568b171a092ea078f790bf4f7fe#body_text
is schema:about of	named entity 'PtdSer' named entity 'virion' named entity 'transferrin receptor 1' named entity 'Arenavirus' named entity 'cell type' named entity 'phosphate' named entity 'Alphavirus' named entity 'wild-type' named entity 'BAI1' named entity 'clathrin-mediated endocytosis' named entity 'T-cells' named entity 'Vero cells' named entity 'repeat regions' named entity 'integrins' named entity 'encode proteins' named entity 'PtdSer' named entity 'Vaccinia virus' named entity 'glycoprotein' named entity 'caveolin' named entity 'Ebola' named entity 'viral life cycle' named entity 'PtdSer' named entity 'HaCaT' named entity 'Rhabdovirus' named entity 'glycoprotein' named entity 'MFG-E8' named entity 'Old World' named entity 'anti-apoptotic' named entity 'Receptor' named entity 'plasma' named entity 'infection' named entity 'cellular compartment' named entity 'mucosal' named entity 'TIM-4' named entity 'LASV' named entity 'macrophages' named entity 'Rhabdovirus' named entity 'virion' named entity 'Arenavirus' named entity 'flaviviruses' named entity 'PtdSer' named entity 'Vesicular stomatitis virus' named entity 'flavivirus' named entity 'PtdSer' named entity 'pseudotyped' named entity 'liposomes' named entity 'Immune cells' named entity 'protein' named entity 'ligands' named entity 'IL-10' named entity 'PtdSer' named entity 'virus-like particles' named entity 'extracellular' named entity 'thrombospondin' named entity 'lymph node' named entity 'Machupo virus' named entity 'binding domain' named entity 'Alphavirus' named entity 'Rhabdovirus' named entity 'BAI1' named entity 'crystal structure' named entity 'adaptive immunity' named entity 'Ligand binding' named entity 'interact' named entity 'dendritic cells' named entity 'PtdSer' named entity 'Tissues' named entity 'Rhabdovirus' named entity 'adapter proteins' named entity 'IgV' named entity 'alphavirus' named entity 'IgV domain' named entity 'de Souza' named entity 'glycoprotein' named entity 'ligands' named entity 'Dengue Virus' named entity 'vaccinia virus' named entity 'filoviruses' named entity 'apoptosis' named entity 'macropinocytosis'

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