About: SARS-CoV-2 Infection Among Symptom-Free Healthcare Workers

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	SARS-CoV-2 Infection Among Symptom-Free Healthcare Workers
Creator	Kline, Susan De Hoff, Peter Demmer, Ryan Belda-Ferre, Pedro Marotz, Clarisse Ulrich, Angela Affiliations, ; Laurent, Louise Stovitz, Steven Humphrey, Greg Knight, ; Kulasingam, Shalini Naumchik, Brianna Strickland, Ali Wiggen, Talia
Source	MedRxiv; Medline
abstract	Importance: Current evidence suggests that transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is possible among symptom-free individuals but limited data are available on this topic in healthcare workers (HCW). The quality and acceptability of self-collected nasopharyngeal swabs (NPS) is unknown. Objective: To estimate the prevalence of SARS-CoV-2 infection and to assess the acceptability of self-collected NPS among HCW. Design: Cross-sectional convenience sample enrolled between April 20th and June 24th, 2020. We had >95% power to detect at least one positive test if the true underlying prevalence of SARS-CoV2 was > 1%. Setting: The metropolitan area surrounding Minneapolis and St. Paul, Minnesota. Participants: HCW free of self-reported upper respiratory symptoms were recruited. Exposures: Participants completed questionnaires regarding demographics, household characteristics, personal protective equipment (PPE) utilization and comorbidities. Outcomes: A participant self-collected nasopharyngeal swab (NPS) was obtained. SARS-CoV-2 infection was assessed via polymerase chain reaction. NPS discomfort was assessed on a scale of 1 (no discomfort) - 10 (extreme discomfort). NPS duration and depth into the nasopharynx, and willingness to perform future self-collections were assessed. Results: Among n=489 participants 80% were female and mean age+/-SD was 41+/-11. Participants reported being physicians (14%), nurse practitioners (8%), physicians assistants (4%), nurses (51%), medics (3%), or other which predominantly included laboratory technicians and administrative roles (22%). Exposure to a known/suspected COVID-19 case in the 14 days prior to enrollment was reported in 40% of participants. SARS-CoV-2 was not detected in any participant. The mean+/-SD discomfort level of the NPS was 4.5+/-2.0. 95% of participants reported that their self-swab was longer than or equal to the duration of patient swabs they had previously performed, and 89% reported the depth to be deeper than or equal to the depth of previous patient swabs. Over 95% of participants reported a willingness to repeat a self-collected NP swab in the future. Conclusions and Relevance: The point prevalence of SARS-CoV-2 infection was likely very low in symptom-free Minnesota healthcare workers from April 20th and June 24th, 2020. Self-collected NP swabs are well-tolerated and a viable alternative to provider-collected swabs to preserve PPE.
has issue date	2020-08-04(xsd:dateTime)
bibo:doi	10.1101/2020.07.31.20166066
bibo:pmid	32793921
has license	medrxiv
sha1sum (hex)	400d8f54b412c4acb36af14d71257833982e09e4
schema:url	https://doi.org/10.1101/2020.07.31.20166066
resource representing a document's title	SARS-CoV-2 Infection Among Symptom-Free Healthcare Workers
has PubMed identifier	32793921
schema:publication	medRxiv : the preprint server for health sciences
resource representing a document's body	covid:400d8f54b412c4acb36af14d71257833982e09e4#body_text
is schema:about of	covid:arg/400d8f54b412c4acb36af14d71257833982e09e4 named entity 'Workers' named entity 'Word Count' named entity 'Symptom' named entity 'SARS-CoV-2' named entity 'laboratory testing' named entity 'nasopharyngeal swab' named entity 'PPE' named entity 'symptom' named entity 'symptom' named entity 'nasopharynx' named entity 'Healthcare workers' named entity 'UC San Diego' named entity 'PPE' named entity 'ethanol' named entity 'Institutional Review Board' named entity 'seroprevalence' named entity 'health care' named entity 'SARS-CoV-2' named entity 'convenience sample' named entity 'reaction plates' named entity 'PPE' named entity 'chills' named entity 'exposure to the virus' named entity 'PPE' named entity 'severe acute respiratory syndrome coronavirus 2' named entity 'nucleic acid' named entity 'infection' named entity 'screening tests' named entity 'Positive controls' named entity 'HCW' named entity 'Minnesota' named entity 'Nucleic Acid' named entity 'nasal congestion' named entity 'research purposes' named entity 'general population' named entity 'HCW' named entity 'H2O' named entity 'clinical diagnostic' named entity 'SARS-CoV-2' named entity 'symptom' named entity 'Figures' named entity 'nasopharyngeal swab' named entity 'healthcare workers' named entity 'June 24' named entity 'WORD' named entity 'infection' named entity 'HCW' named entity 'Centers for Disease Control' named entity 'healthcare workers' named entity 'ThermoFisher Scientific' named entity 'Minneapolis' named entity 'community transmission' named entity 'point prevalence' named entity 'symptom' named entity 'HCW' named entity 'infection' named entity 'PPE' named entity 't-tests' named entity '95%' named entity 'symptom' named entity 'nasopharynx' named entity 'reagent' named entity 'RNA' named entity 'nasopharyngeal swabs' named entity 'RT-qPCR' named entity 'healthcare facilities' named entity '95%'

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