About: Elimination of Porcine Epidemic Diarrhea Virus in an Animal Feed Manufacturing Facility

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Elimination of Porcine Epidemic Diarrhea Virus in an Animal Feed Manufacturing Facility
Creator	Bai, Jianfa Poulsen, Elizabeth Cochrane, Roger Jones, Cassandra Huss, Anne Schumacher, Loni Dritz, Steve Stark, Charles Woodworth, Jason
Source	Medline; PMC
abstract	Porcine Epidemic Diarrhea Virus (PEDV) was the first virus of wide scale concern to be linked to possible transmission by livestock feed or ingredients. Measures to exclude pathogens, prevent cross-contamination, and actively reduce the pathogenic load of feed and ingredients are being developed. However, research thus far has focused on the role of chemicals or thermal treatment to reduce the RNA in the actual feedstuffs, and has not addressed potential residual contamination within the manufacturing facility that may lead to continuous contamination of finished feeds. The purpose of this experiment was to evaluate the use of a standardized protocol to sanitize an animal feed manufacturing facility contaminated with PEDV. Environmental swabs were collected throughout the facility during the manufacturing of a swine diet inoculated with PEDV. To monitor facility contamination of the virus, swabs were collected at: 1) baseline prior to inoculation, 2) after production of the inoculated feed, 3) after application of a quaternary ammonium-glutaraldehyde blend cleaner, 4) after application of a sodium hypochlorite sanitizing solution, and 5) after facility heat-up to 60°C for 48 hours. Decontamination step, surface, type, zone and their interactions were all found to impact the quantity of detectable PEDV RNA (P < 0.05). As expected, all samples collected from equipment surfaces contained PEDV RNA after production of the contaminated feed. Additionally, the majority of samples collected from non-direct feed contact surfaces were also positive for PEDV RNA after the production of the contaminated feed, emphasizing the potential role dust plays in cross-contamination of pathogen throughout a manufacturing facility. Application of the cleaner, sanitizer, and heat were effective at reducing PEDV genomic material (P < 0.05), but did not completely eliminate it.
has issue date	2017-01-18(xsd:dateTime)
bibo:doi	10.1371/journal.pone.0169612
bibo:pmid	28099453
has license	cc-by
sha1sum (hex)	40a57ffe8adda95a13b552b630b13d76344f666c
schema:url	https://doi.org/10.1371/journal.pone.0169612
resource representing a document's title	Elimination of Porcine Epidemic Diarrhea Virus in an Animal Feed Manufacturing Facility
has PubMed Central identifier	PMC5242487
has PubMed identifier	28099453
schema:publication	PLoS One
resource representing a document's body	covid:40a57ffe8adda95a13b552b630b13d76344f666c#body_text
is schema:about of	named entity 'contained' named entity 'reduce' named entity 'feeds' named entity 'solution' named entity 'residual' named entity 'sanitize' named entity 'collected' named entity 'contamination' named entity 'feed' named entity 'facility' named entity 'feed' named entity 'Measures' named entity 'virus' named entity 'exclude' named entity 'production' named entity 'Animal' named entity 'UP TO' named entity 'RESIDUAL' named entity 'PORCINE EPIDEMIC DIARRHEA VIRUS' named entity 'SURFACE' named entity 'INTERACTIONS' named entity 'PATHOGEN' named entity 'MANUFACTURING FACILITY' named entity 'MAJORITY' named entity 'FINISHED' named entity 'PLAYS' named entity 'DID' named entity 'FEEDS' named entity 'QUATERNARY AMMONIUM' named entity 'REDUCING' named entity 'IMPACT' named entity 'EVALUATE' named entity 'SCALE' named entity 'PURPOSE' named entity 'GENOMIC MATERIAL' named entity '9AC' named entity 'VIRUS' named entity 'SOLUTION' named entity 'TREATMENT' named entity 'THEIR' named entity '48 HOURS' named entity 'ELIMINATION' named entity 'PORCINE EPIDEMIC DIARRHEA VIRUS' named entity 'ANIMAL FEED' named entity 'PREVENT' named entity 'HEAT' named entity 'REDUCE' named entity '0.05' named entity 'LIVESTOCK FEED' named entity 'DIRECT' named entity 'LOAD' named entity 'GLUTARALDEHYDE' named entity 'CONTAINED' named entity 'LEAD' named entity 'MANUFACTURING FACILITY' named entity 'FAR' named entity 'AS EXPECTED' named entity 'EXCLUDE' named entity 'NON-' named entity 'CONCERN' named entity 'COLLECTED' named entity 'ACTUAL' named entity 'PROTOCOL' named entity 'COMPLETELY' named entity 'EXPERIMENT' named entity 'ZONE' named entity 'RESEARCH' named entity 'DECONTAMINATION' named entity 'FOUND' named entity 'MEASURES' named entity 'SWABS' named entity 'BEING' named entity 'SAMPLES'

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