About: Circulating microRNAs in malaria infection: bench to bedside

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Circulating microRNAs in malaria infection: bench to bedside
Creator	Chamnanchanunt, Supat Fucharoen, Suthat Umemura, Tsukuru
Source	PMC
abstract	Severe malaria has a poor prognosis with a morbidity rate of 80% in tropical areas. The early parasite detection is one of the effective means to prevent severe malaria of which specific treatment strategies are limited. Many clinical characteristics and laboratory testings have been used for the early diagnosis and prediction of severe disease. However, a few of these factors could be applied to clinical practice. MicroRNAs (miRNAs) were demonstrated as useful biomarkers in many diseases such as malignant diseases and cardiovascular diseases. Recently it was found that plasma miR-451 and miR-16 were downregulated in malaria infection at parasitic stages or with multi-organ failure involvement. MiR-125b, -27a, -23a, -150, 17–92 and -24 are deregulated in malaria patients with multiple organ failures. Here, the current findings of miRNAs were reviewed in relation to clinical severity of malaria infection and emphasized that miRNAs are potential biomarkers for severe malaria infection.
has issue date	2017-08-15(xsd:dateTime)
bibo:doi	10.1186/s12936-017-1990-x
bibo:pmid	28807026
has license	cc-by
sha1sum (hex)	40d43a9724eba1ff38172686caa6f64def12ba7c
schema:url	https://doi.org/10.1186/s12936-017-1990-x
resource representing a document's title	Circulating microRNAs in malaria infection: bench to bedside
has PubMed Central identifier	PMC5557074
has PubMed identifier	28807026
schema:publication	Malar J
resource representing a document's body	covid:40d43a9724eba1ff38172686caa6f64def12ba7c#body_text
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