About: Ebola virus entry into host cells: identifying therapeutic strategies

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About: Ebola virus entry into host cells: identifying therapeutic strategies Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Ebola virus entry into host cells: identifying therapeutic strategies
Creator	Maury, Wendy Rhein, Bethany
Source	Medline; PMC
abstract	Filoviruses cause severe hemorrhagic fever in humans. The archetypal virus of this group, Ebola virus, is responsible for the current filovirus epidemic in West Africa. Filoviruses infect most mammalian cells, resulting in broad species tropism and likely contributing to rapid spread of virus throughout the body. A thorough understanding of filovirus entry events will facilitate the development of therapeutics against these critical steps in the viral life cycle. This review summarizes the current understanding of filovirus entry and discusses some of the recent advancements in therapeutic strategies that target entry.
has issue date	2015-07-01(xsd:dateTime)
bibo:doi	10.1007/s40588-015-0021-3
bibo:pmid	26509109
has license	bronze-oa
sha1sum (hex)	416fda9bb2411e60413dd167fb7ef3fd56faf07a
schema:url	https://doi.org/10.1007/s40588-015-0021-3
resource representing a document's title	Ebola virus entry into host cells: identifying therapeutic strategies
has PubMed Central identifier	PMC4617201
has PubMed identifier	26509109
schema:publication	Current Clinical Microbiology Reports
resource representing a document's body	covid:416fda9bb2411e60413dd167fb7ef3fd56faf07a#body_text
is schema:about of	named entity 'current' named entity 'Therapeutic' named entity 'FILOVIRUSES' named entity 'VIRUS' named entity 'STRATEGIES' named entity 'FILOVIRUS' named entity 'SPREAD' named entity 'EVENTS' named entity 'RECENT' named entity 'ENTRY INTO HOST' named entity 'STEPS' named entity 'HUMANS' named entity 'THERAPEUTICS' named entity 'CELLS' named entity 'VIRAL LIFE CYCLE' named entity 'INFECT' named entity 'EBOLA VIRUS' named entity 'STRATEGIES' named entity 'THERAPEUTIC' named entity 'IDENTIFYING' named entity 'WEST AFRICA' named entity 'BODY' named entity 'EBOLA VIRUS' named entity 'VIRUS ENTRY' named entity 'SEVERE' named entity 'RESPONSIBLE' named entity 'HEMORRHAGIC FEVER' named entity 'EPIDEMIC' named entity 'RESULTING IN' named entity 'TARGET' named entity 'LIKELY' named entity 'DEVELOPMENT' named entity 'REVIEW' named entity 'CAUSE' named entity 'TROPISM' named entity 'CONTRIBUTING' named entity 'HOST CELLS' named entity 'THESE' named entity 'CRITICAL' named entity 'BROAD' named entity 'ENTRY' named entity 'SPECIES' named entity 'UNDERSTANDING' named entity 'RAPID' named entity 'GROUP' named entity 'MAMMALIAN' named entity 'THERAPEUTIC' named entity 'CURRENT' named entity 'therapeutic' named entity 'summarizes' named entity 'Virus' named entity 'virus' named entity 'filovirus' named entity 'Host Cells' named entity 'AMPK' named entity 'GP2' named entity 'Calmodulin' named entity 'clathrin-dependent endocytosis' named entity 'EBOV' named entity 'refolding' named entity 'endosomal trafficking' named entity 'siRNA' named entity 'influenza virus' named entity 'cell surface proteins' named entity 'interact' named entity 'N-linked glycans' named entity 'filovirus' named entity 'NPC1' named entity 'proteolytically cleaved' named entity 'EBOV' named entity 'antibodies' named entity 'filoviruses' named entity 'filovirus' named entity 'NPC1' named entity 'proteolytically processed' named entity 'RNA editing' named entity 'entry process' named entity 'Filovirus' named entity 'virions' named entity '19, 20'

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