About: A Case-Control Study of Acute Respiratory Tract Infection in General Practice Patients in The Netherlands

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	A Case-Control Study of Acute Respiratory Tract Infection in General Practice Patients in The Netherlands
Creator	Wilbrink, Berry Heijnen, Marie-Louise Van Gageldonk-Lafeber, Arianne Bartelds, Aad Peters, Marcel Van Der Plas, Simone
Source	Medline; PMC
abstract	Background. Acute respiratory tract infections (ARTIs) are responsible for considerable morbidity in the community, but little is known about the presence of respiratory pathogens in asymptomatic individuals. We hypothesized that asymptomatic persons could have a subclinical infection and thus act as a source of transmission. Methods. During the period of 2000–2003, all patients with ARTI who visited their sentinel general practitioner had their data reported to estimate the incidence of ARTI in Dutch general practices. A random selection of these patients (case patients) and an equal number of asymptomatic persons visiting for other complaints (control subjects) were included in a case-control study. Nose and throat swabs of participants were tested for a broad range of pathogens. Results. The overall incidence of ARTI was 545 cases per 10,000 person-years, suggesting that, in the Dutch population, an estimated 900,000 persons annually consult their general practitioner for respiratory complaints. Rhinovirus was most common in case patients (24%), followed by influenza virus type A (11%) and coronavirus (7%). Viruses were detected in 58% of the case patients, β-hemolytic streptococci group A were detected in 11%, and mixed infections were detected in 3%. Pathogens were detected in ∼30% of control subjects, particularly in the youngest age groups. Conclusion. This study confirms that most ARTIs are viral and supports the reserved policy of prescribing antibiotics. In both case and control subjects, rhinovirus was the most common pathogen. Of bacterial infections, only group A β-hemolytic streptococci were more common in case patients than in control subjects. Furthermore, we demonstrated that asymptomatic persons might be a neglected source of transmission.
has issue date	2005-08-15(xsd:dateTime)
bibo:doi	10.1086/431982
bibo:pmid	16028157
has license	no-cc
sha1sum (hex)	42527efa8f07be148d1efc4f7b1bdefc3a3e7520
schema:url	https://doi.org/10.1086/431982
resource representing a document's title	A Case-Control Study of Acute Respiratory Tract Infection in General Practice Patients in The Netherlands
has PubMed Central identifier	PMC7107976
has PubMed identifier	16028157
schema:publication	Clin Infect Dis
resource representing a document's body	covid:42527efa8f07be148d1efc4f7b1bdefc3a3e7520#body_text
is schema:about of	named entity 'GENERAL PRACTICE' named entity 'individuals' named entity 'THE NETHERLANDS' named entity 'SOURCE' named entity 'RESPIRATORY PATHOGENS' named entity 'RESPIRATORY TRACT INFECTIONS' named entity 'COMMUNITY' named entity 'LITTLE' named entity 'BUT' named entity 'ACUTE RESPIRATORY TRACT INFECTION' named entity 'CASE-CONTROL STUDY' named entity 'MORBIDITY' named entity 'TRANSMISSION' named entity 'ASYMPTOMATIC' named entity 'PATIENTS' named entity 'KNOWN' named entity 'INDIVIDUALS' named entity 'BACKGROUND' named entity 'SUBCLINICAL INFECTION' named entity 'PRESENCE OF' named entity 'ABOUT' named entity 'ACT' named entity 'CONSIDERABLE' named entity 'ACUTE' named entity 'RESPONSIBLE' named entity 'HAVE' named entity 'PERSONS' covid:arg/42527efa8f07be148d1efc4f7b1bdefc3a3e7520 named entity 'asymptomatic' named entity 'transmission' named entity 'hypothesized' named entity 'persons' named entity 'Patients' named entity 'asymptomatic' named entity 'respiratory tract infections' named entity 'subclinical infection' named entity 'asymptomatic' named entity 'The Netherlands' named entity 'viruses' named entity 'influenza' named entity 'Bilthoven' named entity 'respiratory syncytial virus' named entity 'ILI' named entity 'headache' named entity 'C. psittaci' named entity 'control subjects' named entity 'ILI' named entity 'cough' named entity 'Pathogens' named entity 'common cold' named entity 'elderly persons' named entity 'viruses' named entity 'Netherlands' named entity 'questionnaire' named entity 'control subjects' named entity 'Fever' named entity 'influenza viruses' named entity 'hemolytic' named entity 'nose and throat' named entity 'pathogens' named entity 'Primary Health Care' named entity 'ILI' named entity 'antibiotics' named entity 'commensal' named entity 'case-control study' named entity 'control subjects' named entity 'viruses' named entity 'microorganisms' named entity 'influenza virus' named entity 'control subjects' named entity 'statistically significantly' named entity 'Dutch' named entity 'influenza virus' named entity 'older age' named entity 'pathogen' named entity 'chemotherapeutics'

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