About: Prolonged Persistence of PCR-detectable Virus During an Outbreak of SARS-CoV-2 in an Inpatient Geriatric Psychiatry Unit in King County, Washington

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About: Prolonged Persistence of PCR-detectable Virus During an Outbreak of SARS-CoV-2 in an Inpatient Geriatric Psychiatry Unit in King County, Washington Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Prolonged Persistence of PCR-detectable Virus During an Outbreak of SARS-CoV-2 in an Inpatient Geriatric Psychiatry Unit in King County, Washington
Creator	Jerome, Keith Greninger, Alexander Dellit, Timothy Cohen, Seth Lynch, John Corcorran, Maria Mph, M Neme, Santiago Roxby, Alison Nasenbeny, Keri Olin, Svaya Cic, R Constantino-Shor, Cheri Holmes, Holmes, Charity Newman, Gretchen Quinnan-Hostein, Laura Solan, William Bsn Rn, Mha Bsn, Cheri Cmsrn, Charity Cmsrn, Crni Cnml, Rn-Bc Constantino-Shor, Crni Golo, Rani Mhp, Keri Mhp, Rn-Bc Msn, Rn-Bc Nasenbeny, Mha Snoeyenbos Newman, Gretchen
Source	Elsevier; Medline; PMC
abstract	BACKGROUND: We describe key characteristics, interventions, and outcomes of a SARS-CoV-2 outbreak within an inpatient geriatric psychiatry unit at the University of Washington Medical Center – Northwest (UWMC – NW). METHODS: After identifying two patients with SARS-CoV-2 infection on March 11, 2020, we conducted an outbreak investigation and employed targeted interventions including: screening of patients and staff; isolation and cohorting of confirmed cases; serial testing; and enhanced infection prevention measures. RESULTS: We identified 10 patients and 7 staff members with SARS-CoV-2 infection. Thirty percent of patients (n=3) remained asymptomatic over the course of infection. Among SARS-CoV-2 positive patients, fever (n=5, 50%) and cough (n=4, 40%) were the most common symptoms. Median duration of RT-PCR positivity was 25.5 days (IQR 22.8 – 41.8) among symptomatic patients and 22.0 days (IQR 19.5 – 25.5) among asymptomatic patients. Median initial (19.0, IQR 18.7 – 25.7 vs. 21.7, IQR 20.7 – 25.6) and nadir (18.9, IQR 18.2 – 20.3 vs. 19.8, IQR 17.0 – 20.7) cycle threshold values were similar across symptomatic and asymptomatic patients, respectively. CONCLUSIONS: Asymptomatic infection was common in this cohort of hospitalized, elderly individuals despite similar duration of SARS-CoV-2 RT-PCR positivity and cycle threshold values among symptomatic and asymptomatic patients.
has issue date	2020-08-20(xsd:dateTime)
bibo:doi	10.1016/j.ajic.2020.08.025
bibo:pmid	32827597
has license	no-cc
sha1sum (hex)	43005aba131aa10629fde71d56f22aaf368d285d
schema:url	https://doi.org/10.1016/j.ajic.2020.08.025
resource representing a document's title	Prolonged Persistence of PCR-detectable Virus During an Outbreak of SARS-CoV-2 in an Inpatient Geriatric Psychiatry Unit in King County, Washington
has PubMed Central identifier	PMC7438365
has PubMed identifier	32827597
schema:publication	Am J Infect Control
resource representing a document's body	covid:43005aba131aa10629fde71d56f22aaf368d285d#body_text
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