About: Beneficial effects of probiotics in upper respiratory tract infections and their mechanical actions to antagonize pathogens

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Beneficial effects of probiotics in upper respiratory tract infections and their mechanical actions to antagonize pathogens
Creator	Carton, T Courau, S Crociani, J Dufour, C Le Vacon, F »more»
source	Medline; PMC
abstract	Probiotics are live micro‐organisms with beneficial effects on human health, which have the ability to counteract infections at different locations of the body. Clinical trials have shown that probiotics can be used as preventive and therapeutic agents in upper respiratory tract infections (URTIs) and otitis. Their mechanical properties allow them to aggregate and to compete with pathogens for nutrients, space and attachment to host cells. Consequently, they can directly antagonize pathogens and thus exert beneficial effects without directly affecting the metabolism of the host. An overview of the probiotics with such traits, tested up to date in clinical trials for the prevention or treatment of URTIs and otitis, is presented in this review. Their mechanical properties in the respiratory tract as well as at other locations are also cited. Species with interesting in vitro properties towards pharyngeal cells or against common respiratory pathogens have also been included. The potential safety risks of the cited species are then discussed. This review could be of help in the screening of probiotic strains with specific mechanical properties susceptible to have positive effects in clinical trials against URTIs.
has issue date	2012-08-03(xsd:dateTime)
bibo:doi	10.1111/j.1365-2672.2012.05394.x
bibo:pmid	22788970
has license	no-cc
sha1sum (hex)	43e2cfbc39a597d2a3b90bc0c12819aab9eabc8f
schema:url	https://doi.org/10.1111/j.1365-2672.2012.05394.x
resource representing a document's title	Beneficial effects of probiotics in upper respiratory tract infections and their mechanical actions to antagonize pathogens
has PubMed Central identifier	PMC7166318
has PubMed identifier	22788970
schema:publication	J Appl Microbiol
resource representing a document's body	covid:43e2cfbc39a597d2a3b90bc0c12819aab9eabc8f#body_text
is schema:about of	named entity 'PHARYNGEAL' named entity 'probiotics' named entity 'effects on human health' named entity 'host cells' named entity 'pathogens' »more»

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