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About:
Convalescent plasma therapy in patients with COVID‐19
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An Entity of Type :
schema:ScholarlyArticle
, within Data Space :
wasabi.inria.fr
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document(s)
Type:
Academic Article
research paper
schema:ScholarlyArticle
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type
Academic Article
research paper
schema:ScholarlyArticle
isDefinedBy
Covid-on-the-Web dataset
has title
Convalescent plasma therapy in patients with COVID‐19
Creator
Baştürk, Abdülkadir
Dal, Sinan
Dal, Tuba
Erkurt, Ali
Fevzi Altuntaş, |
Geno Glu, Yi
Glu, Hacıbekiro
Glu, Namdaro
Gçe Nur, Tu
Ilhami Berber, |
Mehmet, |
Serdal Korkmaz, |
Sinem, |
Tuba, |
Turgut, Burhan
Ulas, Turgay
Source
Medline; PMC; WHO
abstract
There are currently no licensed vaccines or therapeutics for COVID‐19. Anti‐SARS CoV‐2 antibody‐containing plasmas, obtained from the recovered individuals who had confirmed COVID‐19, have been started to be collected using apheresis devices and stored in blood banks in some countries in order to administer to the patients with COVID‐19 for reducing the need of intensive care and the mortality rates. Therefore, in this review, we aim to point out some important issues related to convalescent plasma (CP) and its use in COVID‐19. CP may be an adjunctive treatment option to the anti‐viral therapy. The protective effect of CP may continue for weeks and months. After the assessment of the donor, 200‐600 mL plasma can be collected with apheresis devices. The donation interval may vary between countries. Even though limited published studies are not prospective or randomized, until the development of vaccines or therapeutics, CP seems to be a safe and probably effective treatment for critically ill patients with COVID‐19. It could also be used for prophylactic purposes but the safety and effectiveness of this approach should be tested in randomized prospective clinical trials.
has issue date
2020-07-09
(
xsd:dateTime
)
bibo:doi
10.1002/jca.21806
bibo:pmid
32643200
has license
no-cc
sha1sum (hex)
43eb8c64089f303d53f8928e952914396e86ea22
schema:url
https://doi.org/10.1002/jca.21806
resource representing a document's title
Convalescent plasma therapy in patients with COVID‐19
has PubMed Central identifier
PMC7361338
has PubMed identifier
32643200
schema:publication
J Clin Apher
resource representing a document's body
covid:43eb8c64089f303d53f8928e952914396e86ea22#body_text
is
schema:about
of
named entity 'therapeutics'
named entity 'LICENSED'
named entity 'MORTALITY RATES'
named entity 'ISSUES'
named entity 'PATIENTS'
named entity 'ORDER TO ADMINISTER'
named entity 'ADJUNCTIVE TREATMENT'
named entity 'ANTIBODY'
named entity 'COVID-19'
named entity 'individuals'
named entity 'patients'
named entity 'blood banks'
named entity 'COVID-19'
named entity 'SARS CoV'
named entity 'blood banks'
named entity 'COVID-19'
named entity 'anti-viral therapy'
named entity 'mortality rates'
named entity 'Convalescent plasma therapy'
named entity 'COVID'
named entity 'COVID'
named entity 'SARS-CoV-2'
named entity 'blood oxygen saturation'
named entity 'RNA'
named entity 'RT-PCR'
named entity 'SARS-CoV-2'
named entity 'infection'
named entity 'apheresis'
named entity 'intravenous immunoglobulin'
named entity 'ribavirin'
named entity 'apheresis'
named entity 'transfusion'
named entity 'WHO'
named entity '1:160'
named entity 'comorbidities'
named entity 'antibody'
named entity 'SARS-CoV-2'
named entity 'titer'
named entity 'COVID-19'
named entity 'American Food and Drug Administration'
named entity 'Nobel Prize'
named entity 'transfusion'
named entity 'immunological'
named entity 'ABO blood group'
named entity 'global outbreak'
named entity 'Respiratory Syncytial Virus'
named entity 'antibodies'
named entity 'randomized controlled clinical trials'
named entity 'COVID-19'
named entity '1:160'
named entity 'seroconversion'
named entity 'observational studies'
named entity '2019-nCoV'
named entity 'pneumonia'
named entity 'antibody titer'
named entity 'chronic obstructive pulmonary disease'
named entity 'RNA'
named entity 'clinical research'
named entity 'SARS-CoV-2'
named entity 'antibody'
named entity 'apheresis'
named entity 'prophylactic'
named entity 'IgA'
named entity 'TRALI'
named entity 'clinical symptoms'
named entity 'solvent'
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