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  • Liquorice has an active substance, Glycyrrhizin which inhibits the conversion of precursor cortisol to cortisone by inhibiting the enzyme 11-betahydroxysteroid dehydrogenase. When imbibed, liquorice acts like hyperaldosteronism which presents with typical symptoms including high blood pressure, low blood potassium, and muscle pain and weakness. This article appraises physiological and pharmacological effects on health of liquorice, critiques products containing liquorice, describes a typical case report of liquorice-induced hypertension, and appraises oral effects from consumption of liquorice products.
Subject
  • Liquorice
  • Glycyrrhiza
  • Clinical research
  • Medicinal plants
  • 11β-Hydroxysteroid dehydrogenase inhibitors
  • Electrolyte disturbances
  • Plants used in Ayurveda
  • Sugar substitutes
  • Demulcents
  • Indian spices
  • Monoamine oxidase inhibitors
  • Plants described in 1753
  • Plants used in traditional Chinese medicine
  • Spices
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