About: Effects of host genetic variations on response to, susceptibility and severity of respiratory infections

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About: Effects of host genetic variations on response to, susceptibility and severity of respiratory infections Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Effects of host genetic variations on response to, susceptibility and severity of respiratory infections
Creator	Pyrc, Krzysztof Sanak, Marek Branicki, Wojciech Ghafouri-Fard, Soudeh Noroozi, Rezvan Taheri, Mohammad Poṡpiech, Ewelina Vafaee, Reza Davood Omrani, Mir
Source	Elsevier; Medline; PMC
abstract	The recent outbreak of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has created a global crisis, necessitating the identification of genetic factors that modulate the risk of disorder or its severity. The current data about the role of genetic risk factors in determination of rate of SARS-CoV-2 infection in each ethnic group and the severity of disorder is limited. Moreover, several confounding parameters such as the number of tests performed in each country, the structure of the population especially the age distribution, the presence of risk factors for respiratory disorders such as smoking and other environmental factors might be involved in the variability in disease course or prevalence of infection among different ethnic groups. However, assessment of the role of genetic variants in determination of the course of other respiratory infections might help in recognition of possible candidate for further analysis in patients affected with SARS-CoV-2. In the current review, we summarize the data showing the association between genomic variants and risk of acute respiratory distress syndrome, respiratory infections or severity of these conditions with an especial focus on the SARS-CoV-2.
has issue date	2020-05-29(xsd:dateTime)
bibo:doi	10.1016/j.biopha.2020.110296
bibo:pmid	32480226
has license	no-cc
sha1sum (hex)	44ad5b23b316b3c2f85c0c9ad55f0a9b6f082a16
schema:url	https://doi.org/10.1016/j.biopha.2020.110296
resource representing a document's title	Effects of host genetic variations on response to, susceptibility and severity of respiratory infections
has PubMed Central identifier	PMC7258806
has PubMed identifier	32480226
schema:publication	Biomed Pharmacother
resource representing a document's body	covid:44ad5b23b316b3c2f85c0c9ad55f0a9b6f082a16#body_text
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