About: Molecular epidemiology of KI and WU polyomaviruses in infants with acute respiratory disease and in adult hematopoietic stem cell transplant recipients

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About: Molecular epidemiology of KI and WU polyomaviruses in infants with acute respiratory disease and in adult hematopoietic stem cell transplant recipients Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Molecular epidemiology of KI and WU polyomaviruses in infants with acute respiratory disease and in adult hematopoietic stem cell transplant recipients
Creator	Nava, Stefano Canducci, Filippo Clementi, Massimo Debiaggi, Maurizia Brerra, Roberto Sampaolo, Michela Alessandrino, Emilio Arghittu, Milena Marinozzi, Maria Nucleo, Elisabetta Parea, Maurizio Romero, Egidio
source	Medline; PMC
abstract	Polyomaviruses KI (KIPyV) and WU (WUPyV) were described recently in children with acute respiratory disease. The pathogenic potential of these human viruses has not been determined completely, but a correlation between immunosuppression and virus reactivation has been suggested. In the present study, the association between KI/WUPyV infection and immunosuppression was investigated using sequential nasopharyngeal aspirates from asymptomatic adult hematopoietic stem cell transplant recipients. In parallel, an investigation on the WU/KIPyV prevalence in children with acute respiratory disease was also carried out. Two of the 126 samples obtained from the 31 hematopoietic transplant recipients were positive for KIPyV (1 sample, 0.79%) and WUPyV (1 sample, 0.79%). Both samples were obtained 15 days after allogeneic transplantation and virus persistence was not observed in subsequent samples. In symptomatic children, 7 of the 486 nasopharyngeal aspirates were positive for WUPyV (1.4%) and 1 for KIPyV (0.2%). Single polyomavirus infection was detected in four patients, whereas the remaining patients were co‐infected with respiratory syncityal virus (three patients) or adenovirus (one patient). The results suggest that WU/KIPyVs have a limited circulation in Italy and a low pathogenic potential in young children. Brief and asymptomatic infection can occur in hematopoietic transplant recipients. J. Med. Virol. 82:153–156, 2010. © 2009 Wiley‐Liss, Inc.
has issue date	2009-11-30(xsd:dateTime)
bibo:doi	10.1002/jmv.21659
bibo:pmid	19950241
has license	no-cc
sha1sum (hex)	45508bba9b66a681a314d273abe1432d0678db90
schema:url	https://doi.org/10.1002/jmv.21659
resource representing a document's title	Molecular epidemiology of KI and WU polyomaviruses in infants with acute respiratory disease and in adult hematopoietic stem cell transplant recipients
has PubMed Central identifier	PMC7166565
has PubMed identifier	19950241
schema:publication	J Med Virol
resource representing a document's body	covid:45508bba9b66a681a314d273abe1432d0678db90#body_text
is schema:about of	named entity 'Respiratory Disease' named entity 'Infants' named entity 'Molecular' named entity 'viruses' named entity 'Policlinico San Matteo' named entity 'long-term' named entity 'pathogens' named entity 'viruses' named entity 'pathogens' named entity 'allogeneic' named entity 'human metapneumovirus' named entity 'immunosuppression' named entity 'hRSV' named entity 'DNA sequences' named entity 'respiratory diseases' named entity 'polyomaviruses' named entity 'molecular epidemiology' named entity 'respiratory diseases' named entity 'viruses' named entity 'virus shedding' named entity 'informed consent' named entity 'hMPV' named entity 'nasopharyngeal' named entity 'respiratory disease' named entity 'polyomaviruses' named entity 'polyomaviruses' named entity 'nucleic acids' named entity 'viruses' named entity 'immunocompromised' named entity 'opportunistic pathogens' named entity 'follow-up studies' named entity 'immunocompromised' named entity 'Qiagen' named entity 'hematopoietic stem cell transplantation' named entity 'immunocompetent' named entity 'respiratory infection' named entity 'influenza A and B viruses' named entity 'Italy' named entity 'respiratory diseases' named entity 'viruses' named entity 'infection' named entity 'Hematology' named entity 'Hilden' named entity 'PCR' named entity 'respiratory symptoms' named entity 'co-infection' named entity 'parainfluenza' named entity 'aspirates' named entity 'primers' named entity 'LTAg' named entity 'viruses' named entity 'immunocompromised patients' named entity 'gene' named entity 'human respiratory syncytial virus' named entity 'asymptomatic patients' named entity 'bronchitis' named entity 'respiratory disease' named entity 'Viral' named entity 'infection' named entity 'hospital practice' named entity 'human coronaviruses' named entity 'fever' named entity 'allogeneic' named entity 'Italian' named entity 'hRSV' named entity 'gene' named entity 'Foster City' named entity 'co-infection' named entity 'aspirates' named entity 'genomic DNA'

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