About: Detection of the nucleocapsid protein of severe acute respiratory syndrome coronavirus in serum: Comparison with results of other viral markers

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About: Detection of the nucleocapsid protein of severe acute respiratory syndrome coronavirus in serum: Comparison with results of other viral markers Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Detection of the nucleocapsid protein of severe acute respiratory syndrome coronavirus in serum: Comparison with results of other viral markers
Creator	Zhuang, Hui Zhou, Yi-Hua Li, Tong Li, Jie Wang, Ling Li, Yong-Hua Liu, Xue-En
Source	Elsevier; Medline; PMC
abstract	A capture enzyme-enhanced chemiluminescence immunoassay (ECLIA) based on three specific monoclonal antibodies to detect the nucleocapsid (N) protein of severe acute respiratory syndrome (SARS) associated coronavirus (SARS-CoV) in the serial serum samples from SARS patients was developed. The anti-SARS-CoV IgG and the viral RNA were also detected in the sera by ELISA and RT-PCR, respectively. During the first 10 days after onset, anti-SARS-CoV IgG, SARS-CoV RNA and the N protein were detected in 21.4, 42.9, and 90% of the patients’ sera, respectively. The detection rate of the N protein during days 11–15 of the disease was still significantly higher than those of anti-SARS-CoV IgG and SARS-CoV RNA. The data demonstrated that detection of the N protein with the capture ECLIA appears to be more useful than detection of other viral makers for rapid diagnosis of SARS in patients.
has issue date	2005-07-15(xsd:dateTime)
bibo:doi	10.1016/j.jviromet.2005.06.001
bibo:pmid	16024098
has license	no-cc
sha1sum (hex)	45ca2584297a3c3f952d86d8f5392a633881322d
schema:url	https://doi.org/10.1016/j.jviromet.2005.06.001
resource representing a document's title	Detection of the nucleocapsid protein of severe acute respiratory syndrome coronavirus in serum: Comparison with results of other viral markers
has PubMed Central identifier	PMC7112769
has PubMed identifier	16024098
schema:publication	J Virol Methods
resource representing a document's body	covid:45ca2584297a3c3f952d86d8f5392a633881322d#body_text
is schema:about of	named entity 'severe acute respiratory syndrome (SARS)' named entity 'IgG' named entity 'RNA' named entity '42.9' named entity '90%' named entity 'CAPTURE' named entity 'DETECTED' named entity 'CHEMILUMINESCENCE' named entity 'TO DETECT' named entity 'USEFUL' named entity 'PROTEIN ' named entity 'NUCLEOCAPSID' named entity 'ENHANCED' named entity 'DATA' named entity 'SPECIFIC' named entity 'SAMPLES' named entity 'RESULTS' named entity 'PROTEIN ' named entity 'MARKERS' named entity 'ASSOCIATED' named entity 'VIRAL' named entity 'SARS-COV' named entity 'DEMONSTRATED' named entity 'CORONAVIRUS' named entity 'N PROTEIN' named entity 'SERA' named entity 'IGG' named entity 'VIRAL' named entity 'RT-PCR' named entity 'ECLIA' named entity 'MONOCLONAL ANTIBODIES' named entity 'BASED' named entity 'MAKERS' named entity 'RNA' named entity 'VIRAL RNA' named entity 'SERUM' named entity 'DETECTION' named entity 'SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS' named entity 'NUCLEOCAPSID PROTEIN' named entity 'SERUM' named entity 'PATIENTS' named entity 'DETECTION' named entity 'SEVERE ACUTE RESPIRATORY SYNDROME' named entity 'DAYS' named entity 'HIGHER' named entity 'ENZYME' named entity 'COMPARISON' named entity 'ELISA' named entity 'DISEASE' named entity 'SARS' named entity 'ONSET' named entity 'IMMUNOASSAY' named entity 'RAPID DIAGNOSIS' named entity 'SERIAL' named entity 'RATE' covid:arg/45ca2584297a3c3f952d86d8f5392a633881322d named entity 'immunoassay' named entity 'detection' named entity 'During' named entity 'data' named entity 'patients' named entity 'demonstrated' named entity 'Comparison' named entity 'RT-PCR' named entity 'coronavirus' named entity 'SARS-CoV' named entity 'enzyme' named entity 'severe acute respiratory syndrome' named entity 'enhanced chemiluminescence' named entity 'viral RNA' named entity 'SARS-CoV' named entity 'SARS-CoV' named entity 'IgG' named entity 'nucleocapsid' named entity 'nucleocapsid'

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