About: Viral lncRNA: A regulatory molecule for controlling virus life cycle

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About: Viral lncRNA: A regulatory molecule for controlling virus life cycle Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Viral lncRNA: A regulatory molecule for controlling virus life cycle
Creator	Wang, Ziqiang Zhang, Yaou Zhao, Yiwan
topic	covid:464f7d3a460eb51dbc25bd12639b22079a73f85a#this
source	Elsevier; Medline; PMC
abstract	Long non-coding RNAs (lncRNAs) are found not only in mammals but also in other organisms, including viruses. Recent findings suggest that lncRNAs play various regulatory roles in multiple major biological and pathological processes. During viral life cycles, lncRNAs are involved in a series of steps, including enhancing viral gene expression, promoting viral replication and genome packaging, boosting virion release, maintaining viral latency and assisting viral transformation; additionally, lncRNAs antagonize host antiviral innate immune responses. In contrast to proteins that function in viral infection, lncRNAs are expected to be novel targets for the modulation of all types of biochemical processes due to their broad characteristics and profound influence. This review highlights our current understanding of the regulatory roles of lncRNAs during viral infection processes with an emphasis on the potential usefulness of lncRNAs as a target for viral intervention strategies, which could have therapeutic implications for the application of a clinical approach for the treatment of viral diseases.
has issue date	2017-03-23(xsd:dateTime)
bibo:doi	10.1016/j.ncrna.2017.03.002
bibo:pmid	30159419
has license	cc-by-nc-nd
sha1sum (hex)	464f7d3a460eb51dbc25bd12639b22079a73f85a
schema:url	https://doi.org/10.1016/j.ncrna.2017.03.002
resource representing a document's title	Viral lncRNA: A regulatory molecule for controlling virus life cycle
has PubMed Central identifier	PMC6096409
has PubMed identifier	30159419
schema:publication	Noncoding RNA Res
resource representing a document's body	covid:464f7d3a460eb51dbc25bd12639b22079a73f85a#body_text
is http://vocab.deri.ie/void#inDataset of	proxy:http/ns.inria.fr/covid19/464f7d3a460eb51dbc25bd12639b22079a73f85a
is schema:about of	named entity 'FUNCTION' named entity 'INTERVENTION STRATEGIES' named entity 'VIRAL DISEASES' named entity 'ENHANCING' named entity 'STEPS' named entity 'TYPES' named entity 'FINDINGS' named entity 'VIRAL INFECTION' named entity 'OUR' named entity 'PROTEINS' named entity 'NOVEL' named entity 'INVOLVED' named entity 'VARIOUS' named entity 'ASSISTING' named entity 'PLAY' named entity 'TREATMENT' named entity 'ROLES' named entity 'LIFE CYCLES' named entity 'POTENTIAL' named entity 'BUT' named entity 'FOUND' named entity 'VIRAL TRANSFORMATION' named entity 'PACKAGING' named entity 'highlights' named entity 'Recent' named entity 'viral diseases' named entity 'viral infection' named entity 'influence' covid:arg/464f7d3a460eb51dbc25bd12639b22079a73f85a named entity 'VIRUSES' named entity 'MAMMALS' named entity 'HAVE' named entity 'BROAD' named entity 'VIRUS' named entity 'CONTROLLING' named entity 'REGULATORY' named entity 'APPLICATION' named entity 'DUE TO' named entity 'MAJOR' named entity 'CONTRAST' named entity 'CURRENT' named entity 'REGULATORY' named entity 'LNCRNA' named entity 'VIRAL' named entity 'THEIR' named entity 'APPROACH' named entity 'BIOCHEMICAL PROCESSES' named entity 'TARGETS' named entity 'RECENT' named entity 'PROMOTING' named entity 'BIOLOGICAL' named entity 'ORGANISMS' named entity 'PROCESSES' named entity 'REVIEW' named entity 'SERIES' named entity 'BOOSTING' named entity 'USEFULNESS' named entity 'ANTIVIRAL' named entity 'CLINICAL' named entity 'SUGGEST' named entity 'LIFE CYCLE' named entity 'VIRAL REPLICATION' named entity 'MULTIPLE' named entity 'VIRAL LATENCY' named entity 'VIRAL GENE EXPRESSION' named entity 'IMMUNE RESPONSES' named entity 'GENOME' named entity 'CHARACTERISTICS' named entity 'MODULATION' named entity 'PATHOLOGICAL PROCESSES' named entity 'INCLUDING' named entity 'HOST' named entity 'MOLECULE' named entity 'THERAPEUTIC' named entity 'INFLUENCE' named entity 'VIRION' named entity 'MAINTAINING'

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