About: Cardiac Function in Kawasaki Disease Patients with Respiratory Symptoms

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Cardiac Function in Kawasaki Disease Patients with Respiratory Symptoms
Source	Medline; PMC
abstract	BACKGROUND AND OBJECTIVES: Respiratory symptoms are often observed in children with Kawasaki disease (KD) during the acute phase. The association of respiratory viruses in children with KD was investigated using multiplex reverse transcriptase-polymerase chain reaction (RT-PCR) and tissue Doppler echocardiography. SUBJECTS AND METHODS: 138 KD patients were included from January 2010 to June 2013. We compared 3 groups (group 1: n=94, KD without respiratory symptoms; group 2: n=44, KD with respiratory symptoms; and group 3: n=50, febrile patients with respiratory symptoms). Laboratory data were obtained from each patient including N-terminal pro-brain natriuretic peptide (NT-proBNP). Echocardiographic measurements were compared between group 1 and group 2. RT-PCR was performed using nasopharyngeal secretion to screen for the presence of 14 viruses in groups 2 and 3. RESULTS: The incidence of KD with respiratory symptoms was 31.8%. The duration of fever was significantly longer, and coronary artery diameter was larger in group 2 than in group 1. Tei index was significantly higher and coronary artery diameter larger in group 2 than group 1. Coronary artery diameter, C-reactive protein levels, platelet count, alanine aminotransferase levels, and NT-pro BNP levels were significantly higher and albumin levels lower in group 2 compared with group 3. CONCLUSION: NT-pro BNP was a valuable diagnostic tool in differentiating KD from other febrile viral respiratory infections. Some viruses were more frequently observed in KD patients than in febrile controls. Tei index using tissue Doppler imaging was increased in KD patients with respiratory symptoms.
has issue date	2015-07-16(xsd:dateTime)
bibo:doi	10.4070/kcj.2015.45.4.317
bibo:pmid	26240586
has license	cc-by-nc
sha1sum (hex)	4776a30b2dc8da97b0c419d7577dd959231bbd61
schema:url	https://doi.org/10.4070/kcj.2015.45.4.317
resource representing a document's title	Cardiac Function in Kawasaki Disease Patients with Respiratory Symptoms
has PubMed Central identifier	PMC4521110
has PubMed identifier	26240586
schema:publication	Korean Circ J
resource representing a document's body	covid:4776a30b2dc8da97b0c419d7577dd959231bbd61#body_text
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