About: Possible Spread of adenovirus type 3 from poultry to humans: indirect evidence from an outbreak in China

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Possible Spread of adenovirus type 3 from poultry to humans: indirect evidence from an outbreak in China
Creator	Wang, Hua Ni, Daxin Li, Liang Wang, Zhongze Bao, Changjun Li, Xian Shi, Zhiyang Dworkin, Jiang, Renjie
Source	Elsevier; PMC
abstract	Abstract Objective To explore the epidemiology and etiology for an outbreak of acute respiratory tract infection that occurred in one county of Jiangsu Province, China 2004. Methods Only cases meeting the case definition were included in the study. We reviewed the medical records of the cases who were admitted to the local hospitals, interviewed cases by a standard questionnaire, and then described the epidemiologic features and analyzed risk factors by means of a case-control study. We collected pharyngeal swab specimens and sent them to different laboratories for isolation and culture. The laboratory used different detection methods such as DIF, PCR, electron microscope examination and microneutralization assay, to identify and then type the positive specimens. Results A total of 871 cases were reported during the period from April 18 to July 4, 2004. The distribution of onset times presented two peaks, one in late May and another in middle June. The epidemic occurred mainly in the elementary and junior high schools in ten townships of one county, and the mean age of the cases was 12 years (range 7 months to 18 years). The course of the disease was acute, and was characterized by fever accompanied with sore throat and tonsillitis. The WBC count of cases was normal or elevated. The mean duration of illness was 5 days (range 2 to 12 days). No fatalities from illness were reported. A case-control study indicated that the possible risk factors were close contact with a case and/or poultry before onset and sharing of towels among members of the family. The typical CPE was observed through inoculating pharyngeal swab specimens into the HEP-2 cell cultures in different laboratories. An infection of adenovirus type 3 was verified by detecting positive specimens in different methods. Conclusion This investigation demonstrated that the acute respiratory infection in cases was caused by adenovirus type 3. Cases occurred in over 70 schools in ten townships in 2004, and the route of transmission was possibly close contact with cases or droplet transmission.
has issue date	2007-09-30(xsd:dateTime)
bibo:doi	10.1016/s1007-4376(07)60071-9
has license	els-covid
sha1sum (hex)	4940630ef0d7fedb1071bd36b1290bfa20ad28e7
schema:url	https://doi.org/10.1016/s1007-4376%2807%2960071-9
resource representing a document's title	Possible Spread of adenovirus type 3 from poultry to humans: indirect evidence from an outbreak in China
has PubMed Central identifier	PMC7147890
schema:publication	Journal of Nanjing Medical University
resource representing a document's body	covid:4940630ef0d7fedb1071bd36b1290bfa20ad28e7#body_text
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