About: Correlation of ELISA based with random access serologic immunoassays for identifying adaptive immune response to SARS-CoV-2

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About: Correlation of ELISA based with random access serologic immunoassays for identifying adaptive immune response to SARS-CoV-2 Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Correlation of ELISA based with random access serologic immunoassays for identifying adaptive immune response to SARS-CoV-2
Creator	Rao, Arundhati Chen, Li Wang, Liping Arroliga, Alejandro Nguyen, Nguyen »more»
source	MedRxiv
abstract	Public health emergency of SARS-CoV-2 has facilitated diagnostic testing as a related medical countermeasure against COVID-19 outbreak. Numerous serologic antibody tests have become available through an expedited federal emergency use only process. This paper highlights the analytical characteristic of an ELISA based assay by AnshLabs and three random access immunoassay (RAIA) by DiaSorin, Roche, and Abbott that have been approved for emergency use authorization (EUA), at a tertiary academic center in a low disease-prevalence area. The AnshLabs gave higher estimates of sero-prevalence, over the three RAIA methods. For positive results, AnshLabs had 93.3% and 100% concordance with DiaSorin or Abbott and Roche respectively. For negative results, AnshLabs had 69.7% and 73.0% concordance with DiaSorin and Roche or Abbott respectively. All discrepant samples that were positive by AnshLabs and negative by RAIA tested positive by all-in-one step SARS-CoV-2 Total (COV2T) assay performed on the automated Siemens Advia Centaur XPT analyzer. None of these methods, however, are useful in early diagnosis of SARSCoV- 2.
has issue date	2020-07-08(xsd:dateTime)
bibo:doi	10.1101/2020.07.06.20145938
has license	medrxiv
sha1sum (hex)	4b2439a916d724e156482c6c071394c93b974f0e
schema:url	https://doi.org/10.1101/2020.07.06.20145938
resource representing a document's title	Correlation of ELISA based with random access serologic immunoassays for identifying adaptive immune response to SARS-CoV-2
resource representing a document's body	covid:4b2439a916d724e156482c6c071394c93b974f0e#body_text
is schema:about of	named entity 'RAIA' named entity 'random' named entity 'immunoassays' covid:arg/4b2439a916d724e156482c6c071394c93b974f0e named entity 'medical' »more»

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