About: Relevance of human metapneumovirus in exacerbations of COPD

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Relevance of human metapneumovirus in exacerbations of COPD
Creator	Rohde, G Arinir, U Bauer, T Borg, I Bufe, A Kronsbein, J Rausse, R Schultze-Werninghaus, G
Source	PMC
abstract	BACKGROUND AND METHODS: Human metapneumovirus (hMPV) is a recently discovered respiratory virus associated with bronchiolitis, pneumonia, croup and exacerbations of asthma. Since respiratory viruses are frequently detected in patients with acute exacerbations of COPD (AE-COPD) it was our aim to investigate the frequency of hMPV detection in a prospective cohort of hospitalized patients with AE-COPD compared to patients with stable COPD and to smokers without by means of quantitative real-time RT-PCR. RESULTS: We analysed nasal lavage and induced sputum of 130 patients with AE-COPD, 65 patients with stable COPD and 34 smokers without COPD. HMPV was detected in 3/130 (2.3%) AE-COPD patients with a mean of 6.5 × 10(5 )viral copies/ml in nasal lavage and 1.88 × 10(5 )viral copies/ml in induced sputum. It was not found in patients with stable COPD or smokers without COPD. CONCLUSION: HMPV is only found in a very small number of patients with AE-COPD. However it should be considered as a further possible viral trigger of AE-COPD because asymptomatic carriage is unlikely.
has issue date	2005-12-21(xsd:dateTime)
bibo:doi	10.1186/1465-9921-6-150
bibo:pmid	16371156
has license	cc-by
sha1sum (hex)	4ba79e54ecf81b30b56461a6aec2094eaf7b7f06
schema:url	https://doi.org/10.1186/1465-9921-6-150
resource representing a document's title	Relevance of human metapneumovirus in exacerbations of COPD
has PubMed Central identifier	PMC1334186
has PubMed identifier	16371156
schema:publication	Respir Res
resource representing a document's body	covid:4ba79e54ecf81b30b56461a6aec2094eaf7b7f06#body_text
is schema:about of	named entity 'virus' named entity 'QUANTITATIVE' named entity 'TO INVESTIGATE' covid:arg/4ba79e54ecf81b30b56461a6aec2094eaf7b7f06 named entity 'Since' named entity 'COPD' named entity 'investigate' named entity 'Human metapneumovirus' named entity 'asthma' named entity 'smokers' named entity 'COPD' named entity 'COPD' named entity 'viruses' named entity 'human metapneumovirus' named entity 'COPD' named entity 'virus' named entity 'viral load' named entity 'hMPV' named entity 'viral load' named entity 'hMPV' named entity 'emergency department' named entity 'prospective cohort study' named entity 'RSV' named entity 'cDNA' named entity 'pneumonia' named entity 'nasal lavage' named entity 'sputum' named entity 'cloned' named entity 'clinical characteristics' named entity 'RNA' named entity 'COPD' named entity 'FEV' named entity 'nucleoprotein' named entity 'smokers' named entity 'FEV' named entity 'infectious disease' named entity 'COPD' named entity 'dyspnea' named entity 'control subjects' named entity 'bronchial obstruction' named entity 'phlegm' named entity 'FVC' named entity 'smokers' named entity 'elderly patients' named entity 'sputum' named entity 'lungs' named entity 'acute exacerbation of COPD' named entity 'smokers' named entity 'pack-years' named entity 'controlled study' named entity 'controlled study' named entity 'controlled study' named entity 'hMPV' named entity 'smokers' named entity 'hMPV' named entity 'long term care facilities' named entity 'acute exacerbation' named entity 'prospective cohort' named entity 'COPD' named entity 'sputum' named entity 'COPD' named entity 'smoking cessation' named entity 'viral load' named entity 'infectious agent' named entity 'hMPV' named entity 'hMPV' named entity 'acute exacerbation' named entity 'hMPV' named entity 'normal distribution' named entity 'COPD' named entity 'Rhinovirus' named entity 'Viral load' named entity 'sputum' named entity 'hMPV'

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