About: Pathogens shape sex differences in mammalian aging

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Pathogens shape sex differences in mammalian aging Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Pathogens shape sex differences in mammalian aging
Creator	Fouchet, David Pontier, Dominique Badruna, Adèle Gaillard, Jean-Michel Lemaître, Jean-François Tidière, Morgane
source	Elsevier; Medline; PMC
abstract	ABSTRACT Understanding the origin of sex differences in lifespan and aging patterns remains a salient challenge in both biogerontology and evolutionary biology. Different factors have been studied but the potential influence of pathogens has never been investigated. Sex differences especially in hormones and resource allocation generate a differential response to pathogens and thereby shape sex differences in lifespan or aging. We provide an integrative framework linking host pathogenic environment with both sex-specific selections on immune performance and mortality trajectories. We propose future directions to fill existing knowledge gaps about mechanisms that link sex differences, not only to exposition and sensitivity to pathogens, but also to mortality patterns, whilst emphasizing the urgent need to consider the role of sex in medicine.
has issue date	2020-05-07(xsd:dateTime)
bibo:doi	10.1016/j.pt.2020.05.004
bibo:pmid	32540194
has license	els-covid
sha1sum (hex)	4e5269fc97d900c370cbc332b8f947661a69d333
schema:url	https://doi.org/10.1016/j.pt.2020.05.004
resource representing a document's title	Pathogens shape sex differences in mammalian aging
has PubMed Central identifier	PMC7203054
has PubMed identifier	32540194
schema:publication	Trends Parasitol
resource representing a document's body	covid:4e5269fc97d900c370cbc332b8f947661a69d333#body_text
is schema:about of	named entity 'Understanding' named entity 'patterns' named entity 'resource allocation' named entity 'factors' named entity 'investigated' named entity 'selections' named entity 'existing' named entity 'influence' named entity 'pathogens' named entity 'sex differences' named entity 'Sex differences' named entity 'sex differences' named entity 'resource allocation' named entity 'pathogens' named entity 'Pathogens' named entity 'immune response' named entity 'physiological' named entity 'life-history traits' named entity 'positively correlated' named entity 'age-associated' named entity 'polygyny' named entity 'thymic involution' named entity 'immune responses' named entity 'immunology' named entity 'species richness' named entity 'mammals' named entity 'Longitudinal studies' named entity 'metabolites' named entity 'adaptive immune' named entity 'parasitized' named entity 'reproductive success' named entity 'sex differences' named entity 'immune responses' named entity 'non-territorial' named entity 'testosterone' named entity 'evolution' named entity 'pathogens' named entity 'mammalian species' named entity 'chronic infection' named entity 'pathogens' named entity 'tissue damage' named entity 'biomedical research' named entity 'chamois' named entity 'MHC' named entity 'companion animals' named entity 'fetus' named entity 'vertebrate species' named entity 'inbred' named entity 'hormonal fluctuations' named entity 'pathogens' named entity 'parasitism' named entity 'pathogen' named entity 'sex differences' named entity 'sex hormone' named entity 'pathogens' named entity 'immunosenescence' named entity 'sex differences' named entity 'immunosenescence' named entity 'Estrogen receptors' named entity 'sex differences' named entity 'sexual selection' named entity 'pathogen' named entity 'pathogens' named entity 'testosterone' named entity 'life-history traits' named entity 'rodents' named entity 'disease prevalence' named entity 'adaptive immune' named entity 'immunology' named entity 'herbivores' named entity 'Japan' named entity 'Human T-cell Lymphotropic Virus' named entity 'iteroparous' named entity 'pregnancy' named entity 'biomedical sciences' named entity 'asymptomatic infections'

Faceted Search & Find service v1.13.91 as of Mar 24 2020

Alternative Linked Data Documents: Sponger | ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3229 as of Jul 10 2020, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (94 GB total memory)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2025 OpenLink Software