About: Peripheral Mechanisms II: The Pharmacology of Peripherally Active Antitussive Drugs

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Peripheral Mechanisms II: The Pharmacology of Peripherally Active Antitussive Drugs Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Peripheral Mechanisms II: The Pharmacology of Peripherally Active Antitussive Drugs
Creator	Bertram, F Mcfadzean, I Spina, D
Source	PMC
abstract	Cough is an indispensable defensive reflex. Although generally beneficial, it is also a common symptom of diseases such as asthma, chronic obstructive pulmonary disease, upper respiratory tract infections, idiopathic pulmonary fibrosis and lung cancer. Cough remains a major unmet medical need and although the centrally acting opioids have remained the antitussive of choice for decades, they have many unwanted side effects. However, new research into the behaviour of airway sensory nerves has provided greater insight into the mechanisms of cough and new avenues for the discovery of novel non-opioid antitussive drugs. In this review, the pathophysiological mechanisms of cough and the development of novel antitussive drugs are reviewed.
has issue date	2009-01-01(xsd:dateTime)
bibo:doi	10.1007/978-3-540-79842-2_8
bibo:pmid	18825340
has license	no-cc
sha1sum (hex)	4f335cd687bc1ee361db616b13116ad738cc1aeb
schema:url	https://doi.org/10.1007/978-3-540-79842-2_8
resource representing a document's title	Peripheral Mechanisms II: The Pharmacology of Peripherally Active Antitussive Drugs
has PubMed Central identifier	PMC7122788
has PubMed identifier	18825340
schema:publication	Pharmacology and Therapeutics of Cough
resource representing a document's body	covid:4f335cd687bc1ee361db616b13116ad738cc1aeb#body_text
is schema:about of	named entity 'Mechanisms' named entity 'Pharmacology' named entity 'clinical studies' named entity 'primate' named entity 'distilled water' named entity 'cough' named entity 'cough' named entity 'TRPV1' named entity 'GABA' named entity 'lung' named entity 'blood-brain barrier' named entity 'cough' named entity 'TRPV1' named entity 'cough' named entity 'vagal' named entity 'cough' named entity 'oedema' named entity 'C-fibres' named entity 'neurones' named entity 'experimental studies' named entity 'spinal cord' named entity 'cough' named entity 'cough' named entity 'endocannabinoid' named entity 'antitussive' named entity 'RARs' named entity 'synaptic input' named entity 'tachyphylaxis' named entity 'Transient receptor potential' named entity 'inhibitory neurotransmitter' named entity 'CNS' named entity 'non-selective' named entity 'extrapulmonary' named entity 'capsaicin' named entity 'iodoresiniferatoxin' named entity 'drug administration' named entity 'cough reflex' named entity 'antitussives' named entity 'cough' named entity 'cough' named entity 'epithelial cells' named entity 'opioids' named entity 'ganglia' named entity 'C-fibres' named entity 'afferent' named entity 'physiochemical' named entity 'afferent' named entity 'TRPA' named entity 'cough' named entity 'NGF' named entity 'RAR' named entity 'citric acid' named entity 'C-fibres' named entity 'capsaicin' named entity 'codeine' named entity 'nerve conduction' named entity 'TRPV1' named entity 'antitussive' named entity 'Trevisani' named entity 'TRPV1 antagonists' named entity 'capsaicin' named entity 'codeine' named entity 'metabolism' named entity 'plasticity' named entity 'citric acid' named entity 'mechanism of action' named entity 'neuropeptide' named entity 'cough' named entity 'capsaicin' named entity 'sensory nerves' named entity 'C-fibres' named entity 'antitussive' named entity 'guinea pigs' named entity 'CNS' named entity 'nociceptors' named entity 'bronchoconstriction' named entity 'cough' named entity 'chloride channels' named entity 'mucosal'

Faceted Search & Find service v1.13.91 as of Mar 24 2020

Alternative Linked Data Documents: Sponger | ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3229 as of Jul 10 2020, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (94 GB total memory)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software