About: Association of radiologic findings with mortality of patients infected with 2019 novel coronavirus in Wuhan, China

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About: Association of radiologic findings with mortality of patients infected with 2019 novel coronavirus in Wuhan, China Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Association of radiologic findings with mortality of patients infected with 2019 novel coronavirus in Wuhan, China
Creator	Hu, Yi Yin, Wen Tan, Weijun Tao, Zhaowu Yuan, Mingli
Source	MedRxiv
abstract	Radiologic characteristics of 2019 novel coronavirus (2019-nCoV) infected pneumonia (NCIP) which had not been fully understood are especially important for diagnosing and predicting prognosis. We retrospective studied 27 consecutive patients who were confirmed NCIP, the clinical characteristics and CT image findings were collected, and the association of radiologic findings with mortality of patients was evaluated. 27 patients included 12 men and 15 women, with median age of 60 years (IQR 47-69). 17 patients discharged in recovered condition and 10 patients died in hospital. The median age of mortality group was higher compared to survival group (68 (IQR 63-73) vs 55 (IQR 35-60), P = 0.003). The comorbidity rate in mortality group was significantly higher than in survival group (80% vs 29%, P = 0.018). The predominant CT characteristics consisted of ground glass opacity (67%), bilateral sides involved (86%), both peripheral and central distribution (74%), and lower zone involvement (96%). The median CT score of mortality group was higher compared to survival group (30 (IQR 7-13) vs 12 (IQR 11-43), P = 0.021), with more frequency of consolidation (40% vs 6%, P = 0.047) and air bronchogram (60% vs 12%, P = 0.025). An optimal cutoff value of a CT score of 24.5 had a sensitivity of 85.6% and a specificity of 84.5% for the prediction of mortality. 2019-nCoV was more likely to infect elderly people with chronic comorbidities. CT findings of NCIP were featured by predominant ground glass opacities mixed with consolidations, mainly peripheral or combined peripheral and central distributions, bilateral and lower lung zones being mostly involved. A simple CT scoring method was capable to predict mortality.
has issue date	2020-02-23(xsd:dateTime)
bibo:doi	10.1101/2020.02.22.20024927
has license	medrxiv
sha1sum (hex)	4f8d24c531d2c334969e09e4b5aed66dcc925c4b
schema:url	https://doi.org/10.1101/2020.02.22.20024927
resource representing a document's title	Association of radiologic findings with mortality of patients infected with 2019 novel coronavirus in Wuhan, China
resource representing a document's body	covid:4f8d24c531d2c334969e09e4b5aed66dcc925c4b#body_text
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