About: Effects of Solanum glaucophyllum toxicity on cell proliferation and apoptosis in the small and large intestine of rabbits

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About: Effects of Solanum glaucophyllum toxicity on cell proliferation and apoptosis in the small and large intestine of rabbits Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Effects of Solanum glaucophyllum toxicity on cell proliferation and apoptosis in the small and large intestine of rabbits
Creator	Barbeito, C Fontana, P Gimeno, E Nishida, F Portiansky, E Zanuzzi, C
Source	Elsevier; Medline; PMC
abstract	Abstract Vitamin D regulates mineral homeostases and enterocyte proliferation and differentiation. Hypervitaminosis D generates changes in cell proliferation, differentiation and apoptosis in several organs. We analysed morphometric parameters and proliferative and apoptotic indices in the intestinal epithelium of rabbits with hypervitaminosis D induced by the chronic treatment with the calcinogenic plant Solanum glaucophyllum. Rabbits were treated for 15 or 30days. A group was treated for 15days and led to possible recovery for 30days. Another group was nutritionally restricted for 30days. Morphological, morphometric, proliferative and apoptotic changes were found in the treated animals. Mild atrophy and reduced proliferation was found in the jejunum and ileum. Apoptosis increased in the crypts of the ileum and in the superficial epithelium and crypts of the rectum. Most of the alterations were partially recovered. The possible involvement in these changes of the hypervitaminosis D-like state induced by S. glaucophyllum is discussed.
has issue date	2012-08-31(xsd:dateTime)
bibo:doi	10.1016/j.rvsc.2011.07.018
bibo:pmid	21862088
has license	els-covid
sha1sum (hex)	4fa1a32390258623afec505efc10865ec47e6f07
schema:url	https://doi.org/10.1016/j.rvsc.2011.07.018
resource representing a document's title	Effects of Solanum glaucophyllum toxicity on cell proliferation and apoptosis in the small and large intestine of rabbits
has PubMed Central identifier	PMC7125838
has PubMed identifier	21862088
schema:publication	Research in Veterinary Science
resource representing a document's body	covid:4fa1a32390258623afec505efc10865ec47e6f07#body_text
is schema:about of	named entity 'MORPHOLOGICAL' named entity 'JEJUNUM' named entity 'CELL PROLIFERATION' named entity 'ANIMALS' named entity 'ORGANS' named entity 'MINERAL' named entity 'SOLANUM GLAUCOPHYLLUM' named entity 'RECOVERY' named entity 'DIFFERENTIATION' named entity 'A GROUP' named entity 'MOST OF' named entity 'SUPERFICIAL' named entity 'LIKE' named entity 'RESTRICTED' named entity 'DAYS' named entity 'ATROPHY' named entity 'THESE' named entity 'crypts' named entity 'superficial' named entity 'jejunum' named entity 'SOLANUM GLAUCOPHYLLUM' named entity 'SMALL' named entity 'EPITHELIUM' named entity 'ILEUM' named entity 'TREATED FOR' named entity 'APOPTOSIS' named entity 'ON CELL' named entity 'RECTUM' named entity 'STATE' named entity 'TREATMENT' named entity 'VITAMIN D' named entity 'INVOLVEMENT' named entity 'POSSIBLE' named entity 'INDICES' named entity 'LARGE INTESTINE' named entity 'TOXICITY' named entity 'RABBITS' named entity 'CELL PROLIFERATION' named entity 'EFFECTS' named entity 'RABBITS' named entity 'PROLIFERATIVE' named entity 'APOPTOSIS INCREASED' named entity 'CHANGES' named entity 'ENTEROCYTE' named entity 'PARTIALLY' named entity 'MILD' named entity 'INTESTINAL EPITHELIUM' named entity 'REDUCED' named entity 'CHRONIC' named entity 'LED' named entity 'TREATED' named entity 'HYPERVITAMINOSIS D' named entity 'ALTERATIONS' named entity 'RECOVERED' named entity 'FOUND' named entity 'PARAMETERS' named entity 'GROUP' named entity 'APOPTOSIS' named entity 'APOPTOTIC' named entity 'INDUCED' named entity 'PLANT' named entity 'PROLIFERATION' covid:arg/4fa1a32390258623afec505efc10865ec47e6f07 named entity 'proliferative' named entity 'recovered' named entity 'apoptotic' named entity 'Rabbits' named entity 'differentiation' named entity 'proliferation' named entity 'hypervitaminosis' named entity 'days' named entity 'alterations' named entity 'jejunum' named entity 'epithelium' named entity 'mineral' named entity 'ileum'

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