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About:
Efficacy of face masks and respirators in preventing upper respiratory tract bacterial colonization and co-infection in hospital healthcare workers
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wasabi.inria.fr
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Academic Article
research paper
schema:ScholarlyArticle
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type
Academic Article
research paper
schema:ScholarlyArticle
isDefinedBy
Covid-on-the-Web dataset
has title
Efficacy of face masks and respirators in preventing upper respiratory tract bacterial colonization and co-infection in hospital healthcare workers
Creator
Zhang, Yi
Seale, Holly
Wang, Quanyi
Yang, Peng
Pang, Xinghuo
Ridda, Iman
Shi, Weixian
Rahman, Bayzidur
Gao, Zhanhai
Dwyer, Dominic
Macintyre, C
Moa, Aye
Source
Elsevier; Medline; PMC
abstract
Abstract Objective We compared the efficacy of medical masks (MM) and N95 respirators (N95) in preventing bacterial colonization/infection in healthcare workers (HCWs). Methods A cluster randomized clinical trial (RCT) of 1441 hospital HCWs randomized to medical masks or N95 respirators, and compared to 481 control HCWs, was performed in Beijing, China, during the winter season of 2008–2009. Participants were followed for development of clinical respiratory illness (CRI). Symptomatic subjects were tested for Streptococcus pneumoniae, Bordetella pertussis, Chlamydia pneumoniae, Mycoplasma pneumoniae or Haemophilus influenza type B by multiplex polymerase chain reaction (PCR). Results The rate of bacterial colonization was 2.8% in the N95 group (p=0.02), 5.3% among medical mask users (p<0.01) and 7.5% among the controls (p=0.16). N95 respirators were significantly protective (adjusted RR 0.34, 95% CI: 0.21–0.56) against bacterial colonization. Co-infections of two bacteria or a virus and bacteria occurred in up to 3.7% of HCWs, and were significantly lower in the N95 arm. Conclusions N95 respirators were significantly protective against bacterial colonization, co-colonization and viral-bacterial co-infection. We showed that dual respiratory virus or bacterial-viral co-infections can be reduced by the use of N95 respirators. This study has occupational health and safety implications for health workers.
has issue date
2014-05-31
(
xsd:dateTime
)
bibo:doi
10.1016/j.ypmed.2014.01.015
bibo:pmid
24472436
has license
els-covid
sha1sum (hex)
5001eac4f4d0c8dd5080fe00e0dda42c3e32fff0
schema:url
https://doi.org/10.1016/j.ypmed.2014.01.015
resource representing a document's title
Efficacy of face masks and respirators in preventing upper respiratory tract bacterial colonization and co-infection in hospital healthcare workers
has PubMed Central identifier
PMC7172205
has PubMed identifier
24472436
schema:publication
Preventive Medicine
resource representing a document's body
covid:5001eac4f4d0c8dd5080fe00e0dda42c3e32fff0#body_text
is
schema:about
of
named entity 'infection'
named entity 'colonization'
named entity 'healthcare'
covid:arg/5001eac4f4d0c8dd5080fe00e0dda42c3e32fff0
named entity 'N95'
named entity 'healthcare workers'
named entity 'bacterial colonization'
named entity 'infection'
named entity 'N95'
named entity 'medical masks'
named entity 'bacterial colonization'
named entity 'co-infection'
named entity 'healthcare workers'
named entity 'upper respiratory tract'
named entity 'coronaviruses'
named entity 'polymerase chain reaction'
named entity '3.2%'
named entity 'infection'
named entity 'personal protection'
named entity 'co-infection'
named entity 'modes of transmission'
named entity 'respiratory infection'
named entity 'relative risk'
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named entity 'Korea'
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named entity 'Peng Yang'
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named entity 'multiplex PCR'
named entity 'OC43'
named entity 'meta-analysis'
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named entity 'University of New South Wales'
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named entity 'mode of transmission'
named entity 'Seoul'
named entity 'cluster randomized trial'
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