About: Fabrication of Metal Incorporated Polymer Composite: An Excellent Antibacterial Agent

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Fabrication of Metal Incorporated Polymer Composite: An Excellent Antibacterial Agent
Creator	Dar, Ahmad Ahamad, Irshad Akram, Tasneem Dar, Fatma, Fatma, Athar Hashmi, Ikbal, Md Iqbal, Sajid Malik, Ahmad Ovas, Ahmad Talukdar, Ahmed
source	Elsevier; Medline; PMC
abstract	Abstract US Food and Drug Administration (FDA) allowed for direct addition of castor oil for human consumption as food and most recently FDA approved castor oil as over-the-counter (OTC) for laxative drug. The present article highlights the green route phosphorylation of castor oil (COL) via condensation polymerization. Further, the incorporation of metal ions Cu (II)) and Zn (II) into the polymer matrix have been carried out at elevated temperature using catalyst p-toluene sulphonic acid (PTSA). The modification of the said material has been confirmed by FT-IR, UV-VIS, and 1H and 31P-NMR spectroscopy. Further, the in vitro antibacterial activities of the metal incorporated-COL has been performed by standard methods against Bacillus cereus (MCC2243) (gram-positive) and Escherichia coli (MCC2412) (gram-negative) bacteria. The results revealed that the incorporation of metal ions into the polymer matrix increases the antibacterial activity largely. This may be governed by the electrostatic interaction between metal ions and microbes also the generation of free active oxygen hinders the normal activity of bacteria. These results suggest that the synthesized material may act a potential candidate for low cost, environment friendly antibacterial agents and may find their application in clinical fields. Herein we are also proposing mechanism of antibacterial activity.
has issue date	2020-08-14(xsd:dateTime)
bibo:doi	10.1016/j.molstruc.2020.129091
bibo:pmid	32834117
has license	els-covid
sha1sum (hex)	502603a17f8e58e05d2c2d6eb3d71d4b39743fdd
schema:url	https://doi.org/10.1016/j.molstruc.2020.129091
resource representing a document's title	Fabrication of Metal Incorporated Polymer Composite: An Excellent Antibacterial Agent
has PubMed Central identifier	PMC7428313
has PubMed identifier	32834117
schema:publication	Journal of Molecular Structure
resource representing a document's body	covid:502603a17f8e58e05d2c2d6eb3d71d4b39743fdd#body_text
is schema:about of	named entity 'Fabrication' named entity 'global warming' named entity 'sulphonic acid' named entity 'phosphorylation' named entity 'polymers' named entity 'polymerization' named entity 'metal ions' named entity 'FDA' named entity 'p-27' named entity 'castor oil' named entity 'radical species' named entity 'polymer' named entity 'magnetic susceptibility' named entity 'broad peak' named entity 'direct addition' named entity 'PTSA' named entity 'zinc' named entity 'scientific society' named entity 'RNA' named entity 'human consumption' named entity 'condensation polymerization' named entity 'antibacterial activity' named entity 'antibacterial' named entity 'Bacillus cereus' named entity 'polymer matrix' named entity 'condensation polymerization' named entity 'molecular weight distribution' named entity 'metal ion' named entity 'molecular weight' named entity 'charge transfer' named entity 'laxative' named entity 'UV spectrum' named entity 'UV-VIS' named entity 'antigen' named entity 'OTC' named entity 'copper' named entity 'NMR spectroscopy' named entity 'polymers' named entity 'antibacterial' named entity 'polypeptides' named entity 'US Food and Drug Administration' named entity 'polyesters' named entity 'toluene' named entity 'petrochemicals' named entity 'ion' named entity 'castor' named entity 'metal ion' named entity 'over-the-counter' named entity 'antibacterial' named entity 'pharmacokinetic' named entity 'castor oil' named entity 'FDA' named entity 'Polymer Composite' named entity 'Antibacterial Agent' named entity 'Composite' named entity 'Antibacterial' named entity 'Polymer' named entity 'Incorporated'
is part of of	Fabrication of Metal Incorporated Polymer Composite: An Excellent Antibacterial Agent covid:502603a17f8e58e05d2c2d6eb3d71d4b39743fdd#body_text Abstract US Food and Drug Administration (FDA) allowed for direct addition of castor oil for human consumption as food and most recently FDA approved castor oil as over-the-counter (OTC) for laxative drug. The present article highlights the green route phosphorylation of castor oil (COL) via condensation polymerization. Further, the incorporation of metal ions Cu (II)) and Zn (II) into the polymer matrix have been carried out at elevated temperature using catalyst p-toluene sulphonic acid (PTSA). The modification of the said material has been confirmed by FT-IR, UV-VIS, and 1H and 31P-NMR spectroscopy. Further, the in vitro antibacterial activities of the metal incorporated-COL has been performed by standard methods against Bacillus cereus (MCC2243) (gram-positive) and Escherichia coli (MCC2412) (gram-negative) bacteria. The results revealed that the incorporation of metal ions into the polymer matrix increases the antibacterial activity largely. This may be governed by the electrostatic interaction between metal ions and microbes also the generation of free active oxygen hinders the normal activity of bacteria. These results suggest that the synthesized material may act a potential candidate for low cost, environment friendly antibacterial agents and may find their application in clinical fields. Herein we are also proposing mechanism of antibacterial activity.

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