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About:
A novel group of rhinoviruses is associated with asthma hospitalizations
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schema:ScholarlyArticle
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wasabi.inria.fr
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Type:
Academic Article
research paper
schema:ScholarlyArticle
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type
Academic Article
research paper
schema:ScholarlyArticle
isDefinedBy
Covid-on-the-Web dataset
has title
A novel group of rhinoviruses is associated with asthma hospitalizations
Creator
Edwards, Kathryn
Lu, Xiaoyan
Zhu, Yuwei
Griffin, Marie
Heil, Luke
Morin, Laura-Lee
Iwane, Marika
Williams, John
Miller, E
Hall, Caroline
Szilagyi, Peter
Weinberg, Geoffrey
Source
Elsevier; Medline; PMC
abstract
Background Although recent studies have identified new group C human rhinoviruses (HRVCs), their spectrum of pediatric disease is unknown. Objective We sought to determine the presentation and burden of disease caused by HRVCs among young hospitalized children. Methods We conducted prospective population-based surveillance in 2 US counties among children less than 5 years of age hospitalized with acute respiratory illness or fever from October 2001 through September 2003. Nasal/throat swabs were obtained and tested for HRVs, as determined by means of RT-PCR and then characterized by means of partial sequencing. Results Of 1052 children enrolled and tested during the 2-year period, 167 (16%) had HRVs detected. Of 147 samples successfully sequenced, 64 were group A HRVs, 6 were group B HRVs, and 77 were HRVCs. Children with HRVCs were significantly more likely than those with group A HRVs to have underlying high-risk conditions, such as asthma (42% vs 23%, P = .023) and to have had a discharge diagnosis of asthma (55% vs 36%, P = .022). Conclusions Overall, HRVCs were detected in 7% of children hospitalized for fever or respiratory conditions and constituted almost half of all rhinovirus-associated hospitalizations, suggesting that this novel group causes a substantial burden of pediatric disease.
has issue date
2009-01-31
(
xsd:dateTime
)
bibo:doi
10.1016/j.jaci.2008.10.007
bibo:pmid
19027147
has license
els-covid
sha1sum (hex)
51ef14bdf6a50af272e0c7d075714cd386f66c77
schema:url
https://doi.org/10.1016/j.jaci.2008.10.007
resource representing a document's title
A novel group of rhinoviruses is associated with asthma hospitalizations
has PubMed Central identifier
PMC7112283
has PubMed identifier
19027147
schema:publication
Journal of Allergy and Clinical Immunology
resource representing a document's body
covid:51ef14bdf6a50af272e0c7d075714cd386f66c77#body_text
is
schema:about
of
named entity 'RHINOVIRUSES'
named entity 'substantial'
named entity 'identified'
named entity 'Methods'
named entity 'hospitalized'
named entity 'NOVEL'
named entity 'CONCLUSIONS'
named entity 'ASSOCIATED'
named entity 'COUNTIES'
named entity 'NEW'
named entity 'BURDEN OF DISEASE'
named entity 'HIGH-RISK'
named entity 'OBJECTIVE'
named entity 'SEQUENCING'
named entity 'GROUP C'
named entity 'DETECTED'
named entity 'THEIR'
named entity 'ASTHMA'
named entity 'PERIOD'
named entity '104'
named entity 'RT-PCR'
named entity '2855'
named entity 'CHILDREN'
named entity 'CAUSED BY'
named entity 'RESPIRATORY'
named entity 'PARTIAL'
named entity 'GROUP'
named entity 'NASAL'
named entity 'HUMAN'
named entity 'DISCHARGE DIAGNOSIS'
named entity 'ALMOST'
named entity 'TESTED'
named entity 'RHINOVIRUS'
named entity 'CAUSES'
named entity 'METHODS'
named entity 'HAVE'
named entity 'HOSPITALIZED CHILDREN'
named entity 'LIKELY'
named entity 'CHARACTERIZED'
named entity 'IMMUNOL'
named entity 'OBTAINED'
named entity 'GROUP'
named entity 'ASTHMA'
named entity 'ALLERGY'
named entity 'HALF'
named entity 'SPECTRUM'
named entity 'ENROLLED'
named entity 'RHINOVIRUSES'
named entity 'ACUTE RESPIRATORY ILLNESS'
named entity 'OCTOBER'
named entity 'UNKNOWN'
named entity 'ASSOCIATED WITH'
named entity 'SEPTEMBER'
named entity 'PRESENTATION'
named entity '167'
named entity 'IDENTIFIED'
named entity 'HOSPITALIZATIONS'
named entity 'POPULATION-BASED'
named entity 'YEAR'
named entity 'RECENT'
named entity 'DETERMINE'
named entity 'DETERMINED BY'
named entity 'PEDIATRIC DISEASE'
named entity 'STUDIES'
named entity 'PROSPECTIVE'
named entity 'GROUP B'
named entity 'TESTED FOR'
named entity 'HOSPITALIZATIONS'
named entity 'YEARS'
named entity 'LESS THAN'
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