About: The effects of ozone on immune function.

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About: The effects of ozone on immune function. Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	The effects of ozone on immune function.
Creator	Canning, Brendan Gilmour2, Matthew Hopkins, Johns Jakab, George Kleeberger, Steven Spannhake, Ernst
Source	Medline; PMC
abstract	A review of the literature reveals that ozone (O3) exposure can either suppress or enhance immune responsiveness. These disparate effects elicited by O3 exposure depend, in large part, on the experimental design used, the immune parameters examined as well as the animal species studied. Despite the apparent contradictions, a general pattern of response to O3 exposure can be recognized. Most studies indicate that continuous O3 exposure leads to an early (days 0-3) impairment of immune responsiveness followed, with continued exposures, by a form of adaptation to O3 that results in a re-establishment of the immune response. The effects of O3 exposure on the response to antigenic stimulation also depend on the time at which O3 exposure occurred. Whereas O3 exposure prior to immunization is without effect on the response to antigen, O3 exposure subsequent to immunization suppresses the response to antigen. Although most studies have focused on immune responses in the lung, numerous investigators have provided functional and anatomical evidence to support the hypothesis that O3 exposure can have profound effects on systemic immunity.
has issue date	1995-03-01(xsd:dateTime)
bibo:pmid	7614952
has license	no-cc
sha1sum (hex)	52ad224b03765bb748a346a5d0586beef490a490
resource representing a document's title	The effects of ozone on immune function.
has PubMed Central identifier	PMC1518840
has PubMed identifier	7614952
schema:publication	Environ Health Perspect
resource representing a document's body	covid:52ad224b03765bb748a346a5d0586beef490a490#body_text
is schema:about of	named entity 'REVIEW OF THE LITERATURE' named entity 'EITHER' named entity 'OZONE' named entity 'EXPERIMENTAL DESIGN' named entity 'EFFECTS' named entity 'THESE' named entity 'EXPOSURE' named entity 'DEPEND' named entity 'ANIMAL SPECIES' named entity 'LARGE' named entity 'USED' named entity 'SUPPRESS' named entity 'IMMUNE PARAMETERS' named entity 'ENHANCE' named entity 'EFFECTS' named entity 'IMMUNE FUNCTION' named entity 'ELICITED BY' named entity 'EXAMINED' named entity 'REVEALS' named entity 'IMMUNE' named entity 'OZONE' named entity 'RESPONSIVENESS' covid:arg/52ad224b03765bb748a346a5d0586beef490a490 named entity 'depend' named entity 'literature' named entity 'immune' named entity 'cell-mediated immune responses' named entity 'mitogenic' named entity 'respiratory infections' named entity 'T-cells' named entity 'human health' named entity 'endogenous infections' named entity 'phagocytosis' named entity 'MLN' named entity 'S. zooepidemicus' named entity 'aerosol' named entity 'lymphocytes' named entity 'ppm' named entity 'mice' named entity 'neoplastic cells' named entity 'host defenses' named entity 'moderate exercise' named entity 'Listeria' named entity 'Listeria' named entity 'ppm' named entity 'Mycoplasma pulmonis' named entity '3, 4' named entity 'ppm' named entity 'ppm' named entity 'immunosuppressive' named entity 'host response' named entity 'BALT' named entity 'serum' named entity 'immune function' named entity 'phagocytosis' named entity 'inhalation' named entity 'toxicology' named entity 'T-cell' named entity 'PHA' named entity 'virus' named entity 'mice' named entity 'mice' named entity 'infection' named entity 'mice' named entity 'opsonized' named entity 'MLN' named entity 'mitogens' named entity 'prostanoids' named entity 'influenza' named entity 'antiviral' named entity 'Ozone' named entity 'antibodies' named entity 'Listeria' named entity 'yeast' named entity 'pathogenesis' named entity 'phagocytosis' named entity 'PHA' named entity 'erythrocytes'

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