About: Bronchoalveolar Interferon-α, Tumor Necrosis Factor-α, Interleukin-1, and Inflammation during Acute Influenza in Pigs: A Possible Model for Humans?

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Bronchoalveolar Interferon-α, Tumor Necrosis Factor-α, Interleukin-1, and Inflammation during Acute Influenza in Pigs: A Possible Model for Humans? Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Bronchoalveolar Interferon-α, Tumor Necrosis Factor-α, Interleukin-1, and Inflammation during Acute Influenza in Pigs: A Possible Model for Humans?
Creator	Arbiza, J Lopez, J Taylor, G
Source	Medline; PMC
abstract	Biologically active interferon-α, tumor necrosis factor-α (TNF-α), and interleukin-1 (IL-1) were detected in bronchoalveolar lavage (BAL) fluids of 3-week-old cesarian-derived colostrum-deprived pigs inoculated with H1N1 influenza virus. Cytokine titers and lung virus titers were significantly higher 18–24 h after inoculation than at 48–72 h after inoculation in all 4 litters of pigs examined. All three cytokines were positively correlated with a 3- to 4-fold increase in BAL cell numbers (P < .036) and with a drastic neutrophil infiltration (24%–77% of BAL cells vs. 0–1.5% in controls) (P < .001). In addition, cytokine production coincided with the onset of general and respiratory symptoms of influenza and with the development of a necrotizing bronchopneumonia. This study is the first demonstration of TNF-α and IL-1 in BAL fluids of a natural influenza virus host. It documents that pigs may be a highly valuable experimental model in human influenza virus pneumonia.
has issue date	1998-04-01(xsd:dateTime)
bibo:doi	10.1086/517398
bibo:pmid	9534986
has license	no-cc
sha1sum (hex)	540f2eaa6e1342ac0756d27fe772022931073484
schema:url	https://doi.org/10.1086/517398
resource representing a document's title	Bronchoalveolar Interferon-α, Tumor Necrosis Factor-α, Interleukin-1, and Inflammation during Acute Influenza in Pigs: A Possible Model for Humans?
has PubMed Central identifier	PMC7109807
has PubMed identifier	9534986
schema:publication	J Infect Dis
resource representing a document's body	covid:540f2eaa6e1342ac0756d27fe772022931073484#body_text
is schema:about of	named entity 'RSV' named entity 'derived' named entity 'Prince' named entity 'respiratory' named entity 'RSV' named entity 'combinatorial' named entity 'virus' named entity 'vaccinia virus' named entity 'interleukin' named entity 'selection' named entity 'combinatorial' named entity 'Gen' named entity 'mice' named entity 'Humans' named entity 'MONOCLONAL ANTIBODIES' named entity '404' named entity 'LABORATORY' named entity 'TUMOR NECROSIS FACTOR' named entity 'ISOLATES' named entity 'GLYCOPROTEIN' named entity 'PLAY' named entity 'SYNCYTIAL' named entity 'PLAQUE REDUCTION NEUTRALIZATION TEST' named entity 'BRUSSELS' named entity 'RSV' named entity 'INTERLEUKIN-1 ' named entity 'EFFECTIVE' named entity 'RESPIRATORY VIRUS' named entity 'INTRODUCED' named entity 'THE LUNGS' named entity 'SCOTLAND' named entity 'immunization' named entity 'Crowe' named entity 'Scotland' named entity '1978' named entity 'respiratory syncytial virus' named entity 'August' named entity 'human' named entity 'directed' named entity 'III' named entity 'tumor' named entity 'produced' named entity 'respiratory' named entity 'Veterinary Medicine' named entity 'Gen' named entity 'phage display' named entity 'mutation' named entity 'glycoprotein' named entity 'monoclonal' named entity 'recombinants' named entity 'infection' named entity 'human' named entity 'Tat' named entity 'interleukin-1' named entity 'J Gen Virol' named entity 'respiratory syncytial virus' named entity 'virus' named entity 'Merelbeke' named entity 'virus' named entity 'RSV' named entity 'regulatory proteins' named entity 'tumor necrosis factor' named entity 'J Gen Virol' named entity 'immunogenicity' named entity 'Vaccine' named entity 'RSV' named entity 'chimpanzees' named entity 'Tumor Necrosis Factor' named entity 'Influenza' named entity 'Virology' named entity 'macroscopic' named entity 'manifes' named entity 'Lung' named entity 'IL-1' named entity 'colostrum' named entity 'viral infections' named entity 'lung tissue' named entity 'TNF-a' named entity 'endotoxin'

Faceted Search & Find service v1.13.91 as of Mar 24 2020

Alternative Linked Data Documents: Sponger | ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3229 as of Jul 10 2020, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (94 GB total memory)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software