About: Previous or coincident infections with suspected Kawasaki disease. Should we change our approach?()()

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Previous or coincident infections with suspected Kawasaki disease. Should we change our approach?()()
Creator	Calvo, Cristina Antón-López, Jordi Fernández-Cooke, Elisa Sánchez-Manubens, Judith Barrios Tascón, Ana Daniel, Carlos Lozano, Grasa
source	PMC
abstract	INTRODUCTION: Kawasaki disease (KD) is a multisystem vasculitis associated with coronary artery abnormalities. Infections could be a trigger of the inflammation. The main aim of this study was to describe the presence of infections in children with KD, and to analyse the clinical characteristics and the presence of coronary abnormalities in these cases. PATIENTS AND METHODS: A retrospective study was performed within the Kawasaki Disease network (KAWA-RACE (2011-2016). An analysis was performed that included patients with positive microbiological findings (PMF) during the acute phase, as well as those with a previous recent infection (PRI) during the 4 weeks preceding KD diagnosis. RESULTS: The study included a total of 621 children with KD, with PMF being found in 101 (16.3%) patients, and a PRI in 107 (17.2%). Significantly less echocardiographic abnormalities were found in the group with a PRI, when compared to those without a PRI (23 vs. 35%, P = .01) and also a lower proportion of overall coronary artery lesions (16 vs. 25%, P = .054). No significant differences were found in the proportion of aneurysms in either of these groups (PRI or PMF) when compared to those without infection. CONCLUSIONS: In the present study, no differences were found in the incidence of coronary aneurysms in either of the groups, with or without PRI or PMF. Therefore, if KD is suspected, appropriate treatment should be started despite having a confirmed infection.
has issue date	2019-03-08(xsd:dateTime)
bibo:doi	10.1016/j.anpede.2018.06.011
has license	no-cc
sha1sum (hex)	551e16d89c30e92132981e2148fbabdc359f2b4c
schema:url	https://doi.org/10.1016/j.anpede.2018.06.011
resource representing a document's title	Previous or coincident infections with suspected Kawasaki disease. Should we change our approach?()()
has PubMed Central identifier	PMC7146762
schema:publication	An Pediatr (Engl Ed)
resource representing a document's body	covid:551e16d89c30e92132981e2148fbabdc359f2b4c#body_text
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