About: Clinical manifestations and outcomes of respiratory syncytial virus infection in adult hospitalized patients

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About: Clinical manifestations and outcomes of respiratory syncytial virus infection in adult hospitalized patients Goto Sponge NotDistinct Permalink

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Clinical manifestations and outcomes of respiratory syncytial virus infection in adult hospitalized patients
Creator	Athipanyasilp, Niracha Horthongkham, Navin Chuaychoo, Benjamas Kaewnaphan, Bualan Kantakamalakul, Wannee Muangman, Nisa Ngamwongwan, Sopita
Source	Elsevier; Medline; PMC
abstract	BACKGROUND: Respiratory syncytial virus (RSV) is an important virus found in adult hospitalized patients. OBJECTIVES: To study the clinical outcomes of hospitalized patients aged ≥ 15 years and diagnosed with RSV infection. STUDY DESIGN: Both retrospective and prospective cohort studies were conducted at a university hospital between May 2014 and December 2015. Results: RSV was detected in 86 of 1562(5.5%) adult hospitalized patients suspected of respiratory viral infection. Sixty-nine patients were included in the study. RSV was detected by RT-PCR (82.6%), IFA (10.1%), and both RT-PCR and IFA (7.3%). Most patients (87.0%) were aged ≥ 50 years. Cardiovascular diseases, pulmonary diseases, immunocompromised hosts, and diabetes were the major comorbidities. The common manifestations were cough (92.8%), dyspnea (91.3%), sputum production (87.0%), tachypnea (75.4%), wheezing (73.9%), and fever (71.0%). Fifty- five patients (79.7%) were diagnosed with pneumonia. Hypoxemia (SpO2 ≤ 92%) was found in 53.6% patients. Twenty-five of 69(36.2%) patients developed respiratory failure and required ventilatory support. Cardiovascular complications were found in 24.6% of patients. Congestive heart failure, acute myocardial infarction (MI), new atrial fibrillation, and supraventricular tachycardia were found in 9(13.0%), 7(10.1%), 4(5.8%), and 3(4.3%) of 69 patients, respectively. Overall mortality was 15.9%. Pneumonia (81.8%) and acute MI (18.2%) were the major causes of death. CONCLUSIONS: Most adult hospitalized patients with RSV infection were of advanced age and had comorbidities. Cardiopulmonary complications were the major causes of death. Management and prevention of RSV infection in these vulnerable groups are necessary.
has issue date	2019-07-03(xsd:dateTime)
bibo:doi	10.1016/j.jcv.2019.07.001
bibo:pmid	31280089
has license	no-cc
sha1sum (hex)	556da7e95cd7fb3a0c95a92e676fe78f0e487019
schema:url	https://doi.org/10.1016/j.jcv.2019.07.001
resource representing a document's title	Clinical manifestations and outcomes of respiratory syncytial virus infection in adult hospitalized patients
has PubMed Central identifier	PMC7106545
has PubMed identifier	31280089
schema:publication	J Clin Virol
resource representing a document's body	covid:556da7e95cd7fb3a0c95a92e676fe78f0e487019#body_text
is schema:about of	named entity 'Study design' named entity '2014' named entity 'HOSPITALIZED PATIENTS' named entity 'VENTILATORY SUPPORT' named entity 'ADVANCED AGE' named entity '2887' named entity 'COUGH' named entity 'DIABETES' named entity 'WHEEZING' named entity 'PULMONARY DISEASES' named entity 'SUPRAVENTRICULAR TACHYCARDIA' named entity '1562' named entity 'UNIVERSITY HOSPITAL' named entity '287' named entity 'RT-PCR' named entity 'VULNERABLE' named entity 'HOSPITALIZED PATIENTS' named entity 'COMMON' named entity '2015' named entity 'ADULT' covid:arg/556da7e95cd7fb3a0c95a92e676fe78f0e487019 named entity '2818' named entity 'PATIENTS' named entity 'PNEUMONIA' named entity 'RESPIRATORY FAILURE' named entity 'SIXTY-NINE' named entity 'RSV' named entity 'YEARS' named entity 'CARDIOVASCULAR COMPLICATIONS' named entity 'OBJECTIVES' named entity 'OVERALL MORTALITY' named entity 'ATRIAL FIBRILLATION' named entity 'MANAGEMENT' named entity 'CONCLUSIONS' named entity 'REQUIRED' named entity 'THESE' named entity 'CLINICAL MANIFESTATIONS' named entity 'RESPIRATORY SYNCYTIAL VIRUS INFECTION' named entity 'TACHYPNEA' named entity 'MANIFESTATIONS' named entity 'PROSPECTIVE COHORT STUDIES' named entity 'PREVENTION OF' named entity 'HOSTS' named entity 'OUTCOMES' named entity '2882' named entity 'FOUND' named entity 'COMORBIDITIES' named entity 'IFA' named entity 'FIFTY' named entity 'ACUTE MYOCARDIAL INFARCTION' named entity 'RSV INFECTION' named entity 'STUDY' named entity 'CONGESTIVE HEART FAILURE' named entity 'NEW' named entity 'IMMUNOCOMPROMISED' named entity 'ADULT' named entity 'NECESSARY' named entity 'HYPOXEMIA' named entity 'TWENTY-FIVE' named entity 'DYSPNEA' named entity 'RETROSPECTIVE' named entity 'RESULTS' named entity 'CARDIOVASCULAR DISEASES' named entity 'CLINICAL OUTCOMES' named entity 'DECEMBER' named entity 'INCLUDED' named entity 'FEVER' named entity 'RESPIRATORY VIRAL INFECTION' named entity 'SPUTUM PRODUCTION' named entity 'ACUTE MI' named entity 'MAJOR' named entity 'STUDY DESIGN' named entity 'SUSPECTED' named entity 'DETECTED' named entity 'CARDIOPULMONARY'

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